PNA Technology (Q79741695)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15004293%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

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title

PNA Technology (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15004293%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Peter E Nielsen

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15004293%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

publication date

1 March 2004

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15004293%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

published in

Molecular Biotechnology

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25 December 2019

volume

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15004293%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

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25 December 2019

page(s)

233-248

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Combination of ATP-bioluminescence and PNA probes allows rapid total counts and identification of specific microorganisms in mixed populations

25 December 2019

cites work

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12 December 2020

Information transfer from peptide nucleic acids to RNA by template-directed syntheses

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12 December 2020

Sequence specific inhibition of DNA restriction enzyme cleavage by PNA.

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12 December 2020

Peptide nucleic acid-mediated PCR clamping as a useful supplement in the determination of microbial diversity

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12 December 2020

Gene delivery by a steroid-peptide nucleic acid conjugate

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12 December 2020

Detection of genetic point mutations by peptide nucleic acid-mediated polymerase chain reaction clamping using paraffin-embedded specimens

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12 December 2020

Polyclonal hematopoiesis with variable telomere shortening in human long-term allogeneic marrow graft recipients

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12 December 2020

PNA beacons for duplex DNA.

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12 December 2020

Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development

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12 December 2020

Peptide nucleic acid: a versatile tool in genetic diagnostics and molecular biology

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12 December 2020

Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA.

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12 December 2020

Peptide nucleic acid (PNA) facilitates multistranded hybrid formation between linear double-stranded DNA targets and RecA protein-coated complementary single-stranded DNA probes

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12 December 2020

Gene chemistry: functionally and conformationally intact fluorescent plasmid DNA.

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12 December 2020

Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain

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12 December 2020

Direct detection and identification of Mycobacterium tuberculosis in smear-positive sputum samples by fluorescence in situ hybridization (FISH) using peptide nucleic acid (PNA) probes

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12 December 2020

Sensitive detection of p53 gene mutations by a 'mutant enriched' PCR-SSCP technique

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12 December 2020

Inhibition of Tat-mediated transactivation of HIV-1 LTR transcription by polyamide nucleic acid targeted to TAR hairpin element

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12 December 2020

Cellular uptake and intracellular fate of antisense oligonucleotides.

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12 December 2020

Peptide nucleic acid (PNA): a model structure for the primordial genetic material?

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12 December 2020

In vivo nuclear delivery of oligonucleotides via hybridizing bifunctional peptides

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12 December 2020

Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes

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12 December 2020

Filter-based PNA in situ hybridization for rapid detection, identification and enumeration of specific micro-organisms

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12 December 2020

Telomerase inhibition by peptide nucleic acids reverses 'immortality' of transformed human cells

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12 December 2020

Unique chromosome identification and sequence-specific structural analysis with short PNA oligomers

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12 December 2020

Template switching between PNA and RNA oligonucleotides

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12 December 2020

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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12 December 2020

Evaluation of a fluorescence in situ hybridization assay for differentiation between tuberculous and nontuberculous Mycobacterium species in smears of Lowenstein-Jensen and Mycobacteria Growth Indicator Tube cultures using peptide nucleic acid probe

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12 December 2020

Modulation of the pharmacokinetic properties of PNA: preparation of galactosyl, mannosyl, fucosyl, N-acetylgalactosaminyl, and N-acetylglucosaminyl derivatives of aminoethylglycine peptide nucleic acid monomers and their incorporation into PNA oligo

1 reference

12 December 2020

Down-regulation of amyloid precursor protein by peptide nucleic acid oligomer in cultured rat primary neurons and astrocytes

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12 December 2020

Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription

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12 December 2020

PNA molecular beacons for rapid detection of PCR amplicons

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12 December 2020

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

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12 December 2020

Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer

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12 December 2020

Single base pair mutation analysis by PNA directed PCR clamping

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12 December 2020

Strand invasion by mixed base PNAs and a PNA-peptide chimera

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12 December 2020

Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli

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12 December 2020

Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers

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12 December 2020

Site-directed recombination via bifunctional PNA-DNA conjugates

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12 December 2020

Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.

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12 December 2020

Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n-myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors

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12 December 2020

Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand

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12 December 2020

Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA.

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12 December 2020

Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

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12 December 2020

Peptide nucleic acids specifically cause antigene effects in vivo by systemic injection

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12 December 2020

Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA.

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12 December 2020

Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells

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12 December 2020

Polyamide nucleic acid targeted to the primer binding site of the HIV-1 RNA genome blocks in vitro HIV-1 reverse transcription

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12 December 2020

Synthesis, uptake, and intracellular metabolism of a hydrophobic tetrapeptide-peptide nucleic acid (PNA)-biotin molecule

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12 December 2020

Heterogeneity in telomere length of human chromosomes.

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12 December 2020

Substituted 1,8-naphthyridin-2(1H)-ones are superior to thymine in the recognition of adenine in duplex as well as triplex structures

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12 December 2020

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

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12 December 2020

Differentiation of Mycobacterium tuberculosis complex and nontuberculous mycobacterial liquid cultures by using peptide nucleic acid-fluorescence In situ hybridization probes

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12 December 2020

Morpholino antisense oligomers: the case for an RNase H-independent structural type

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12 December 2020

Inhibition of NF-κB specific transcriptional activation by PNA strand invasion

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12 December 2020

Enhanced peptide nucleic acid binding to supercoiled DNA: possible implications for DNA "breathing" dynamics

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12 December 2020

Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence

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12 December 2020

Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates

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12 December 2020

In vitro and in vivo studies on the pharmacokinetics and metabolism of PNA constructs in rodents.

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12 December 2020

Peptide nucleic acids as antibacterial agents via the antisense principle

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12 December 2020

Rapid and specific detection of PCR products using light-up probes

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12 December 2020

Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA.

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12 December 2020

Targeted delivery of plasmid DNA to myogenic cells via transferrin-conjugated peptide nucleic acid

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12 December 2020

Genetic analysis by peptide nucleic acid affinity MALDI-TOF mass spectrometry

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12 December 2020

Peptide nucleic acid delivery to human mitochondria

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12 December 2020

Bactericidal antisense effects of peptide-PNA conjugates.

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12 December 2020

Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: sequence-specific suicide transcription

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12 December 2020

Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA.

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12 December 2020

Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells

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12 December 2020

Antisense PNA tridecamers targeted to the coding region of Ha-ras mRNA arrest polypeptide chain elongation

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12 December 2020

Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide

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12 December 2020

High-affinity peptide nucleic acid oligomers containing tricyclic cytosine analogues

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12 December 2020

Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length

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12 December 2020

Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters

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12 December 2020

PNA targeting the PBS and A-loop sequences of HIV-1 genome destabilizes packaged tRNA3(Lys) in the virions and inhibits HIV-1 replication

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12 December 2020

Dihydrotestosterone as a selective cellular/nuclear localization vector for anti-gene peptide nucleic acid in prostatic carcinoma cells

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12 December 2020

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

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12 December 2020

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

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12 December 2020

Peptide nucleic acids rather than RNA may have been the first genetic molecule

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12 December 2020

Study of HIV-2 primer-template initiation complex using antisense oligonucleotides

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12 December 2020

In situ hybridization of Prochlorococcus and Synechococcus (marine cyanobacteria) spp. with RRNA-targeted peptide nucleic acid probes

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12 December 2020

Enhanced strand invasion by peptide nucleic acid-peptide conjugates

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12 December 2020

Cellular uptake of adamantyl conjugated peptide nucleic acids

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12 December 2020

A biological transporter for the delivery of peptide nucleic acids (PNAs) to the nuclear compartment of living cells

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12 December 2020

Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression

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12 December 2020

A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA.

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12 December 2020

Inhibition of promyelocytic leukemia (PML)/retinoic acid receptor-alpha and PML expression in acute promyelocytic leukemia cells by anti-PML peptide nucleic acid

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12 December 2020

Antisense and Antigene Properties of Peptide Nucleic Acids

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12 December 2020

Evidence for (PNA)2/DNA triplex structure upon binding of PNA to dsDNA by strand displacement

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12 December 2020

Defining the peptide nucleic acids (PNA) length requirement for PNA binding-induced transcription and gene expression

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12 December 2020

Affinity purification of DNA and RNA from environmental samples with peptide nucleic acid clamps

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12 December 2020

Affinity capture and recovery of DNA at femtomolar concentrations with peptide nucleic acid probes

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12 December 2020

Increased DNA binding and sequence discrimination of PNA oligomers containing 2,6-diaminopurine

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12 December 2020

Facilitated detection of oncogene mutations from exfoliated tissue material by a PNA-mediated 'enriched PCR' protocol

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12 December 2020

DNA-like double helix formed by peptide nucleic acid

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12 December 2020

Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration

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12 December 2020

A production of amino acids under possible primitive earth conditions

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12 December 2020

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

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12 December 2020

Superior duplex DNA strand invasion by acridine conjugated peptide nucleic acids

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12 December 2020

Additive antisense effects of different PNAs on the in vitro translation of the PML/RARalpha gene

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12 December 2020

Peptide nucleic acid targeting of double-stranded DNA.

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12 December 2020

Information transfer from DNA to peptide nucleic acids by template-directed syntheses

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12 December 2020

Liver cell specific targeting of peptide nucleic acid oligomers

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12 December 2020

Antisense properties of duplex- and triplex-forming PNAs

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12 December 2020

Anti-TAR polyamide nucleotide analog conjugated with a membrane-permeating peptide inhibits human immunodeficiency virus type 1 production

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12 December 2020

A peptide nucleic acid (PNA) is more rapidly internalized in cultured neurons when coupled to a retro-inverso delivery peptide. The antisense activity depresses the target mRNA and protein in magnocellular oxytocin neurons

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12 December 2020

Sequence-specific purification of nucleic acids by PNA-controlled hybrid selection

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12 December 2020

Solid-phase synthesis of peptide nucleic acids

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12 December 2020

Cellular delivery of peptide nucleic acids and inhibition of human telomerase

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12 December 2020

Cell-penetrating peptides.

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12 December 2020

Inhibition of macrophage iNOS by selective targeting of antisense PNA

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12 December 2020

Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BIAcore technique

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12 December 2020

1 reference

12 December 2020

DNA unwinding upon strand-displacement binding of a thymine-substituted polyamide to double-stranded DNA.

1 reference

12 December 2020

PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules

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12 December 2020

Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids

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12 December 2020

Synthesis of Amino- and Guanidino-G-Clamp PNA Monomers

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12 December 2020

Light-up probes: thiazole orange-conjugated peptide nucleic acid for detection of target nucleic acid in homogeneous solution.

1 reference

12 December 2020

Identification of Dekkera bruxellensis (Brettanomyces) from wine by fluorescence in situ hybridization using peptide nucleic acid probes

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12 December 2020

Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future.

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12 December 2020

Inhibition of HIV-1 replication by anti-trans-activation responsive polyamide nucleotide analog

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12 December 2020

Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression

1 reference

12 December 2020

Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal

1 reference

12 December 2020

Rapid detection, identification, and enumeration of Escherichia coli by fluorescence in situ hybridization using an array scanner

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12 December 2020

PNA-mediated purification of PCR amplifiable human genomic DNA from whole blood

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12 December 2020

Free-probe fluorescence of light-up probes

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12 December 2020

Antisense peptide nucleic acids.

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12 December 2020