CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients (Q79456645)

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23 December 2019

title

CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients (English)

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23 December 2019

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23 December 2019

A Caliebe

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L Renders

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23 December 2019

M Frisman

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23 December 2019

M Ufer

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23 December 2019

I Mosyagin

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23 December 2019

S Haenisch

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23 December 2019

U Ott

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23 December 2019

M Dechant

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23 December 2019

F Braun

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23 December 2019

U Kunzendorf

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23 December 2019

publication date

27 December 2006

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Clinical Pharmacology & Therapeutics

23 December 2019

published in

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23 December 2019

volume

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23 December 2019

issue

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23 December 2019

page(s)

228-234

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Cyclosporine nephrotoxicity: how does it affect renal allograft function and transplant morphology?

23 December 2019

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The genetic determinants of the CYP3A5 polymorphism

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The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

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Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy

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Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids

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CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation

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Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients.

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Influence of CYP3A5 and MDR1 polymorphisms on tacrolimus concentration in the early stage after renal transplantation

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CYP3A5*3 influences sirolimus oral clearance in de novo and stable renal transplant recipients.

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7 January 2021

Simultaneous determination of three isomeric metabolites of tacrolimus (FK506) in human whole blood and plasma using high performance liquid chromatography-tandem mass spectrometry

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7 January 2021

Tacrolimus and cerivastatin pharmacokinetics and adverse effects after single and multiple dosing with cerivastatin in renal transplant recipients

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7 January 2021

Influence of different allelic variants of the CYP3A and ABCB1 genes on the tacrolimus pharmacokinetic profile of Chinese renal transplant recipients

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7 January 2021

Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

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7 January 2021

Time to reach tacrolimus maximum blood concentration,mean residence time, and acute renal allograft rejection: an open-label, prospective, pharmacokinetic study in adult recipients

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7 January 2021

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

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7 January 2021

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Identifiers

DOI

10.1038/SJ.CLPT.6100039

1 reference

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23 December 2019

1 reference

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