Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold (Q78181660)

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12 December 2019

title

Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold (English)

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12 December 2019

W C Groutas

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12 December 2019

N M Schechter

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12 December 2019

S He

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12 December 2019

H Yu

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12 December 2019

P Huang

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12 December 2019

J Tu

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12 December 2019

publication date

1 August 1999

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12 December 2019

number of pages

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Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

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12 December 2019

volume

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12 December 2019

issue

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12 December 2019

page(s)

2199-2204

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Serine proteinases of mast cell and leukocyte granules. A league of their own.

12 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

Recombinant expression of human mast cell proteases chymase and tryptase

1 reference

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7 January 2021

Distinct multisite synergistic interactions determine substrate specificities of human chymase and rat chymase-1 for angiotensin II formation and degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

Functional and biochemical analysis of angiotensin II-forming pathways in the human heart

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors

1 reference

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7 January 2021

Peptide boronic acids, substrate analogs, inhibit chymase, and histamine release from rat mast cells

1 reference

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7 January 2021

Peptidyl human heart chymase inhibitors. 1. Synthesis and inhibitory activity of difluoromethylene ketone derivatives bearing P' binding subsites

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

Peptidyl human heart chymase inhibitors. 2. Discovery of highly selective difluoromethylene ketone derivatives with Glu at P3 site

1 reference

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7 January 2021

Substituted 3-(phenylsulfonyl)-1-phenylimidazolidine-2,4-dione derivatives as novel nonpeptide inhibitors of human heart chymase

1 reference

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7 January 2021

Structure-based design of a general class of mechanism-based inhibitors of the serine proteinases employing a novel amino acid-derived heterocyclic scaffold

1 reference

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7 January 2021

Potent and specific inhibition of human leukocyte elastase, cathepsin G and proteinase 3 by sulfone derivatives employing the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

Use of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds in the design of potent inhibitors of serine proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

Crystal Structure of Phenylmethanesulfonyl Fluoride-Treated Human Chymase at 1.9 Å

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2899%2900377-7

7 January 2021

10.1016/S0960-894X(99)00377-7

Identifiers

DOI

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12 December 2019

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