General mechanisms of cytokine receptor signaling (Q77903168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

review article

1 reference

title

General mechanisms of cytokine receptor signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

L R Carpenter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

G D Yancopoulos

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

N Stahl

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

publication date

1 January 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

Advances in Protein Chemistry

9 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

page(s)

109-140

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

Gp130 and the interleukin-6 family of cytokines

9 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

IL-6 cytokine family and signal transduction: a model of the cytokine system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The receptor for ciliary neurotrophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Released Form of CNTF Receptor α Component as a Soluble Mediator of CNTF Responses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Signaling of the cardiotrophin-1 receptor. Evidence for a third receptor component.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Soluble interleukin 6 receptor in biological fluids from human origin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Increased and highly stable levels of functional soluble interleukin-6 receptor in sera of patients with monoclonal gammopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Circulating interleukin-6 receptor in patients with sepsis syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Impaired immune and acute-phase responses in interleukin-6-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

In vitro binding of ciliary neurotrophic factor to its receptors: evidence for the formation of an IL-6-type hexameric complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Interleukin-6: structure-function relationships.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Saturation mutagenesis of the human interleukin 6 receptor-binding site: implications for its three-dimensional structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

JAK protein tyrosine kinases: their role in cytokine signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Cytokine signaling through nonreceptor protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The conserved box 1 motif of cytokine receptors is required for association with JAK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Receptor protein-tyrosine kinases and their signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

An interleukin-4-induced transcription factor: IL-4 Stat

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Essential role of Stat6 in IL-4 signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Interleukin-4-induced STAT6 recognizes and activates a target site in the promoter of the interleukin-4 receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Components of a Stat recognition code: evidence for two layers of molecular selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon alpha/beta-induced gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Coordinate regulation of STAT signaling and c-fos expression by the tyrosine phosphatase SHP-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

A family of cytokine-inducible inhibitors of signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Interferon gamma receptor extracellular domain expressed as IgG fusion protein in Chinese hamster ovary cells. Purification, biochemical characterization, and stoichiometry of binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960434-9

7 January 2021

10.1016/S0065-3233(08)60434-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9917919%20AND%20SRC:MED&resulttype=core&format=json