Advances in drug metabolism screening (Q77420667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10234199%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

Advances in drug metabolism screening (English)

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5 December 2019

Eddershaw PJ

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5 December 2019

Dickins M

series ordinal

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5 December 2019

publication date

1 January 1999

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Pharmaceutical science & technology today

5 December 2019

published in

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5 December 2019

volume

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5 December 2019

issue

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5 December 2019

page(s)

13-19

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High-throughput approaches for evaluating absorption, distribution, metabolism and excretion properties of lead compounds

5 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

In vitro methods for assessing human hepatic drug metabolism: their use in drug development

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Use of in vitro human metabolism studies in drug development. An industrial perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Preclinical drug metabolism in the age of high-throughput screening: an industrial perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Optimization of cryopreservation procedures for rat and human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Prediction of Hepatic Clearance from Microsomes, Hepatocytes, and Liver Slices

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Bioartificial liver support: developments in hepatocyte culture and bioreactor design

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Development of a bioartificial liver using isolated hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Primary cultures of rat hepatocytes in hollow fiber chambers

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

What lessons can be learnt from withdrawal of mibefradil from the market?

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Sodium valproate acutely inhibits lamotrigine metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Prediction of in vivo drug interaction from in vitro systems exemplified by interaction between verapamil and cimetidine using human liver microsomes and primary hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Application of a generic fast gradient liquid chromatography tandem mass spectrometry method for the analysis of cytochrome P450 probe substrates

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

A Microassay for Measuring Cytochrome P450IA1 and Cytochrome P450IIB1 Activities in Intact Human and Rat Hepatocytes Cultured on 96-Well Plates

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Long-term primary cultures of adult human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Phenobarbital induction of cytochrome P-450 gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Modulation of xenobiotic-inducible cytochrome P450 gene expression by dexamethasone in primary rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Distinct effects of phenobarbital and its N-methylated derivative on liver cytochrome P450 induction

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Localization of a phenobarbital-responsive element (PBRE) in the 5′-flanking region of the rat CYP2B2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

Differential Transactivation by Two Isoforms of the Orphan Nuclear Hormone Receptor CAR

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2898%2900108-4

7 January 2021

10.1016/S1461-5347(98)00108-4

Identifiers

DOI

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5 December 2019

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