Three-dimensional representations of G protein-coupled receptor structures and mechanisms (Q74818940)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Three-dimensional representations of G protein-coupled receptor structures and mechanisms (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

13 November 2019

main subject

1 reference

1 reference

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13 November 2019

Irache Visiers

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13 November 2019

Juan A Ballesteros

series ordinal

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13 November 2019

publication date

1 January 2002

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13 November 2019

published in

Methods in Enzymology

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13 November 2019

volume

343

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13 November 2019

page(s)

329-371

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The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.

13 November 2019

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A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif

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7 January 2021

Hinges, swivels and switches: the role of prolines in signalling via transmembrane alpha-helices

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7 January 2021

Modeling of transmembrane seven helix bundles

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7 January 2021

X-ray Structure of Bacteriorhodopsin at 2.5 Angstroms from Microcrystals Grown in Lipidic Cubic Phases

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Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains

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Principles that determine the structure of proteins

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Evolution of protein cores. Constraints in point mutations as observed in globin tertiary structures.

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7 January 2021

Molecular characterization of a functional cDNA encoding the serotonin 1c receptor

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7 January 2021

The guanine nucleotide regulatory protein-coupled receptors for nucleosides, nucleotides, amino acids and amine neurotransmitters

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7 January 2021

Adrenergic receptors as models for G protein-coupled receptors

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7 January 2021

Conformational changes of cytosolic loops of bovine rhodopsin during the transition to metarhodopsin-II: an investigation by Fourier transform infrared difference spectroscopy

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7 January 2021

Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels

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Combined biophysical and biochemical information confirms arrangement of transmembrane helices visible from the three-dimensional map of frog rhodopsin

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7 January 2021

On the spatial disposition of the fifth transmembrane helix and the structural integrity of the transmembrane binding site in the opioid and ORL1 G protein-coupled receptor family

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7 January 2021

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7 January 2021

A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Novel mixed mode Monte Carlo/stochastic dynamics simulations of the complex between TRH and TRH receptor

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7 January 2021

Construction of a 3D model of the cannabinoid CB1 receptor: determination of helix ends and helix orientation

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7 January 2021

Functional Microdomains in G-protein-coupled Receptors

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7 January 2021

The agonist SR 146131 and the antagonist SR 27897 occupy different sites on the human CCK(1) receptor

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7 January 2021

What makes red visual pigments red? A resonance Raman microprobe study of retinal chromophore structure in iodopsin

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7 January 2021

The arrangement of the transmembrane helices in the secretin receptor family of G‐protein‐coupled receptors

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7 January 2021

The Protein Data Bank

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7 January 2021

The relation between the divergence of sequence and structure in proteins

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Challenges at the frontiers of structural biology

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Fold assembly of small proteins using monte carlo simulations driven by restraints derived from multiple sequence alignments.

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7 January 2021

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

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7 January 2021

The role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions

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7 January 2021

Mutational Analysis of the Relative Orientation of Transmembrane Helices I and VII in G Protein-coupled Receptors

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7 January 2021

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7 January 2021

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Prediction of protein structure from sequence

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7 January 2021

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7 January 2021

Comparative modeling and molecular dynamics studies of the delta, kappa and mu opioid receptors

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7 January 2021

Theoretical study on mutation-induced activation of the luteinizing hormone receptor

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Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

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7 January 2021

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

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7 January 2021

A General Method for Mapping Tertiary Contacts between Amino Acid Residues in Membrane-Embedded Proteins

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7 January 2021

Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

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7 January 2021

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

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7 January 2021

Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness

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7 January 2021

Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant

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7 January 2021

Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor

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7 January 2021

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7 January 2021

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7 January 2021

How frequent are correlated changes in families of protein sequences?

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7 January 2021

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Predicting local structural changes that result from point mutations

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Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?

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7 January 2021

Conserved polar residues in the transmembrane domain of the human tachykinin NK2 receptor: functional roles and structural implications

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7 January 2021

The ligand-binding domain of rhodopsin and other G protein-linked receptors

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7 January 2021

Arrangement of transmembrane domains in adrenergic receptors. Similarity to bacteriorhodopsin

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7 January 2021

Modeling of loops in protein structures

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7 January 2021

Molecular dynamics simulations predict a tilted orientation for the helical region of dynorphin A(1-17) in dimyristoylphosphatidylcholine bilayers

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7 January 2021

Sensitivity comparison of protein amino acid sequences

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7 January 2021

Protein sequence alignment techniques.

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7 January 2021

Simultaneous comparison of several sequences

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7 January 2021

Prediction of protein secondary structure at better than 70% accuracy

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7 January 2021

Bridging the protein sequence-structure gap by structure predictions

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7 January 2021

Predicting protein secondary structure with a nearest-neighbor algorithm.

1 reference

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7 January 2021

Patterns of divergence in homologous proteins as indicators of secondary and tertiary structure: a prediction of the structure of the catalytic domain of protein kinases

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7 January 2021

An algorithm for secondary structure determination in proteins based on sequence similarity

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7 January 2021

Differences in conformational properties of the second intracellular loop (IL2) in 5HT(2C) receptors modified by RNA editing can account for G protein coupling efficiency

1 reference

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7 January 2021

Conformational analysis and clustering of short and medium size loops connecting regular secondary structures: a database for modeling and prediction

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7 January 2021

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

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7 January 2021

The Functional Microdomain in Transmembrane Helices 2 and 7 Regulates Expression, Activation, and Coupling Pathways of the Gonadotropin-releasing Hormone Receptor

1 reference

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7 January 2021

A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice

1 reference

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7 January 2021

Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin

1 reference

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7 January 2021

Identification of Conserved Aromatic Residues Essential for Agonist Binding and Second Messenger Production at 5-Hydroxytryptamine2AReceptors

1 reference

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7 January 2021

Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method

1 reference

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7 January 2021

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

1 reference

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7 January 2021

Site-directed mutagenesis of the human dopamine D2 receptor

1 reference

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7 January 2021

The role of conserved aspartate and serine residues in ligand binding and in function of the 5-HT1A receptor: a site-directed mutation study

1 reference

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7 January 2021

Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments

1 reference

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7 January 2021

Specific tryptophan UV-absorbance changes are probes of the transition of rhodopsin to its active state

1 reference

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7 January 2021

Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment

1 reference

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7 January 2021

Ligand-induced domain motion in the activation mechanism of a G-protein-coupled receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

1 reference

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7 January 2021

10.1016/S0076-6879(02)43145-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json