Inhibition of p38 MAP kinase during cellular activation results in IFN-gamma-dependent augmentation of IL-12 production by human monocytes/macrophages (Q74263598)

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scientific article published on 01 July 2001

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English	Inhibition of p38 MAP kinase during cellular activation results in IFN-gamma-dependent augmentation of IL-12 production by human monocytes/macrophages	scientific article published on 01 July 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11472427%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Inhibition of p38 MAP kinase during cellular activation results in IFN-gamma-dependent augmentation of IL-12 production by human monocytes/macrophages (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11472427%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

J B Marriott

1

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9 November 2019

I A Clarke

2

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9 November 2019

A G Dalgleish

3

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9 November 2019

publication date

1 July 2001

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9 November 2019

Clinical and Experimental Immunology

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9 November 2019

125

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9 November 2019

1

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9 November 2019

64-70

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9 November 2019

Recombinant interleukin 12 cures mice infected with Leishmania major

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

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Alcohol (ethanol) inhibits IL-8 and TNF: role of the p38 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

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Antitumor and antimetastatic activity of interleukin 12 against murine tumors

1 reference

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Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

1 reference

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Impaired interleukin 12 production in human immunodeficiency virus-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

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Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

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Regulation of interleukin 12 p40 expression through an NF-kappa B half-site

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

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The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute ethanol treatment augments interleukin-12 production in activated human monocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

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Identification and characterization of a novel Ets-2-related nuclear complex implicated in the activation of the human interleukin-12 p40 gene promoter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of interleukin-12 p40 transcript by CD40 ligation via activation of nuclear factor-kappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic regulation of the human interleukin-12 p40 promoter by NFkappaB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-alpha: role of the p38 and p42/44 mitogen-activated protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased interleukin-12 serum levels in chronic alcoholism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

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inferred from PubMed ID database lookup

Advanced colorectal cancer is associated with impaired interleukin 12 and enhanced interleukin 10 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

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inferred from PubMed ID database lookup

Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SB202190, a selective inhibitor of p38 mitogen-activated protein kinase, is a powerful regulator of LPS-induced mRNAs in monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

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Interleukin 12 deficiency associated with recurrent infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

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CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

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Potent suppression of IL-12 production from monocytes and dendritic cells during endotoxin tolerance

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of monocyte IL-12 production: augmentation by lymphocyte contact and acute ethanol treatment, inhibition by elevated intracellular cAMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell activation signals up-regulate p38 mitogen-activated protein kinase activity and induce TNF-alpha production in a manner distinct from LPS activation of monocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Interleukin (IL)-2 Receptor β-Chain Subdomains and Shc in p38 Mitogen-activated Protein (MAP) Kinase and p54 MAP Kinase (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11472427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of p38 mitogen-activated protein kinase in IL-1 beta transcription

1 reference

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12 December 2020

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Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response

1 reference

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12 December 2020

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Identifiers

10.1046/J.1365-2249.2001.01574.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11472427%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11472427%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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