DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in (Q63384098)

12 December 2020

DNA replication by bacteriophage T4 proteins. The T4 43, 32, 44–62, And 45 proteins are required for strand displacement synthesis at nicks in duplex DNA

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12 December 2020

Mechanism of DNA chain growth. XV. RNA-linked nascent DNA pieces in Escherichia coli strains assayed with spleen exonuclease

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12 December 2020

A 5' to 3' exonuclease functionally interacts with calf DNA polymerase epsilon

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12 December 2020

Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins

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12 December 2020

Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis

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12 December 2020

Protein-priming of DNA replication

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12 December 2020

Deletions in plasmid pBR322: replication slippage involving leading and lagging strands

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12 December 2020

Discontinuous DNA synthesis by purified mammalian proteins

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12 December 2020

Isolation and characterization of a second RNase H (RNase HII) of Escherichia coli K-12 encoded by the rnhB gene

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12 December 2020

Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae

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12 December 2020

Complete enzymatic synthesis of DNA containing the SV40 origin of replication

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12 December 2020

The ability of DNA polymerase beta to synthesize DNA beyond the gap with displacement of the non-replicated strand

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12 December 2020

DNA synthesis on a double-stranded DNA template by the T4 bacteriophage DNA polymerase and the T4 gene 32 DNA unwinding protein.

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12 December 2020

Enzymatic synthesis of deoxyribonucleic acid. XXXII. Replication of duplex deoxyribonucleic acid by polymerase at a single strand break

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12 December 2020

Strand Displacement during Deoxyribonucleic Acid Synthesis at Single Strand Breaks

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12 December 2020

Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains

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12 December 2020

Ribonuclease H. An Enzyme Degrading the RNA Moiety of DNA-RNA Hybrids

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12 December 2020

Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase

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12 December 2020

Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli

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12 December 2020

Characterization and purification of a phage phi 29-encoded DNA polymerase required for the initiation of replication

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12 December 2020

Structure of replicating DNA molecules of Bacillus subtilis bacteriophage phi 29

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12 December 2020

Structure of protein-containing replicative intermediates of Bacillus subtilis phage phi 29 DNA

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12 December 2020

Helix-destabilizing activity of phi 29 single-stranded DNA binding protein: effect on the elongation rate during strand displacement DNA replication.

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12 December 2020

DNA2 Encodes a DNA Helicase Essential for Replication of Eukaryotic Chromosomes

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12 December 2020

A yeast gene required for DNA replication encodes a protein with homology to DNA helicases

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12 December 2020

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

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12 December 2020

Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene

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12 December 2020

Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

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12 December 2020

Reconstitution of complete SV40 DNA replication with purified replication factors

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12 December 2020

DNA replication fork pause sites dependent on transcription

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12 December 2020

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication

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12 December 2020

A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and processive DNA strand-displacement synthesis

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12 December 2020

A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair

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12 December 2020

A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

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12 December 2020

Repeat expansion--all in a flap?

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12 December 2020

Homologous regions of Fen1 and p21Cip1 compete for binding to the same site on PCNA: a potential mechanism to co-ordinate DNA replication and repair

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12 December 2020

Strand Displacement Associated DNA Synthesis Catalyzed by the Epstein-Barr Virus DNA Polymerase

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12 December 2020

The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21

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12 December 2020

Mcm2 is a target of regulation by Cdc7–Dbf4 during the initiation of DNA synthesis

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12 December 2020

Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII1

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12 December 2020

Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).

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12 December 2020

Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta

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12 December 2020

The DNA replication fork in eukaryotic cells.

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12 December 2020

Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII

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12 December 2020

Homologous recombination is required for the viability of rad27 mutants

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12 December 2020

Architecture of the active DNA polymerase delta.proliferating cell nuclear antigen.template-primer complex

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12 December 2020

Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency

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12 December 2020

Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease

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12 December 2020

The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA.

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12 December 2020

Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1

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12 December 2020

Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta

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12 December 2020

The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nucleases, is essential in vivo

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12 December 2020

Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism

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12 December 2020

Two modes of FEN1 binding to PCNA regulated by DNA.

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12 December 2020

Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair

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12 December 2020

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

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12 December 2020

DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis.

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12 December 2020

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12 December 2020

Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1.

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12 December 2020

Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta

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12 December 2020

The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase

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12 December 2020

Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick

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12 December 2020

Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.

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12 December 2020

Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae

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12 December 2020

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

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12 December 2020

Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability

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12 December 2020

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

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12 December 2020

The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes

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12 December 2020

The protein components and mechanism of eukaryotic Okazaki fragment maturation

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12 December 2020

RNase H2 of Saccharomyces cerevisiae is a complex of three proteins

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12 December 2020

On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing

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12 December 2020

EXO1-A multi-tasking eukaryotic nuclease.

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12 December 2020

Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

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12 December 2020

Genetics of lagging strand DNA synthesis and maturation in fission yeast: suppression analysis links the Dna2-Cdc24 complex to DNA polymerase delta

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12 December 2020

Structural basis for recruitment of human flap endonuclease 1 to PCNA

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12 December 2020

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

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12 December 2020

A network of multi-tasking proteins at the DNA replication fork preserves genome stability

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12 December 2020

Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta

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12 December 2020

Flap endonuclease disengages Dna2 helicase/nuclease from Okazaki fragment flaps

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12 December 2020

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast

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12 December 2020

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

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12 December 2020

Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication

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12 December 2020

Break-induced replication: what is it and what is it for?

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12 December 2020

Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal

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12 December 2020

Dynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiae

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12 December 2020

Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint

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12 December 2020

Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis

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12 December 2020

Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex

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12 December 2020

The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo

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12 December 2020

Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae

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12 December 2020

Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway

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12 December 2020

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta

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12 December 2020

Components of the secondary pathway stimulate the primary pathway of eukaryotic Okazaki fragment processing

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12 December 2020

An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase

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12 December 2020

The DNA Damage Response: Making It Safe to Play with Knives

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12 December 2020

Inviability of aDNA2deletion mutant is due to the DNA damage checkpoint

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12 December 2020

Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2.

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12 December 2020

Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.

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12 December 2020

PCNA binding domains in all three subunits of yeast DNA polymerase δ modulate its function in DNA replication

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12 December 2020

Intrinsic coupling of lagging-strand synthesis to chromatin assembly.

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12 December 2020

Preventing replication stress to maintain genome stability: resolving conflicts between replication and transcription

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12 December 2020

Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes

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12 December 2020

Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA.

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12 December 2020

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12 December 2020

Pif1 family helicases suppress genome instability at G-quadruplex motifs

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12 December 2020

Nuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity

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12 December 2020

Break-induced replication occurs by conservative DNA synthesis

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12 December 2020

Determination of the biochemical properties of full-length human PIF1 ATPase

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12 December 2020

PCNA promotes processive DNA end resection by Exo1.

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12 December 2020

The mini-chromosome maintenance (Mcm) complexes interact with DNA polymerase α-primase and stimulate its ability to synthesize RNA primers

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12 December 2020

Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence

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12 December 2020

Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration.

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12 December 2020

Replicative mechanisms for CNV formation are error prone

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12 December 2020

A saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability

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12 December 2020

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.

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12 December 2020

Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.

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12 December 2020

Visualization of recombination-mediated damage bypass by template switching

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12 December 2020

Regulated eukaryotic DNA replication origin firing with purified proteins

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12 December 2020

Regulation of yeast DNA polymerase δ-mediated strand displacement synthesis by 5'-flaps

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12 December 2020

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.

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12 December 2020

A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands

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12 December 2020

The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication

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12 December 2020

Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes

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12 December 2020

Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability

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12 December 2020

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12 December 2020

Dna2 nuclease-helicase structure, mechanism and regulation by Rpa.

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12 December 2020

MCM: one ring to rule them all.

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12 December 2020

Who Is Leading the Replication Fork, Pol ε or Pol δ?

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12 December 2020

Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1

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12 December 2020

Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation

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12 December 2020

Pif1 removes a Rap1-dependent barrier to the strand displacement activity of DNA polymerase δ.

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12 December 2020

Resolving individual steps of Okazaki-fragment maturation at a millisecond timescale

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12 December 2020

DNA Polymerases Divide the Labor of Genome Replication.

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12 December 2020

Chromosome Duplication in Saccharomyces cerevisiae.

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12 December 2020

Cdc24 Is Essential for Long-range End Resection in the Repair of Double-stranded DNA Breaks

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12 December 2020

Chromatin Constrains the Initiation and Elongation of DNA Replication.

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12 December 2020

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.

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12 December 2020

Pif1-family helicases cooperatively suppress widespread replication-fork arrest at tRNA genes

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12 December 2020

Direct Visualization of RNA-DNA Primer Removal from Okazaki Fragments Provides Support for Flap Cleavage and Exonucleolytic Pathways in Eukaryotic Cells.

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12 December 2020

S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion

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12 December 2020

Eukaryotic DNA Replication Fork.

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12 December 2020

Building up and breaking down: mechanisms controlling recombination during replication

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12 December 2020

The motor activity of DNA2 functions as an ssDNA translocase to promote DNA end resection

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12 December 2020

PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes.

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12 December 2020

Arranging eukaryotic nuclear DNA polymerases for replication: Specific interactions with accessory proteins arrange Pols α, δ, and ϵ in the replisome for leading-strand and lagging-strand DNA replication

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12 December 2020

Dormant origins and fork protection mechanisms rescue sister forks arrested by transcription

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12 December 2020

Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication

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12 December 2020

Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase

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12 December 2020

Mechanism of Lagging-Strand DNA Replication in Eukaryotes

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12 December 2020

Architecture of the Saccharomyces cerevisiae Replisome

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12 December 2020

Coordinating Replication with Transcription

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12 December 2020

The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism

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12 December 2020

The mechanism of eukaryotic CMG helicase activation.

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12 December 2020

Break-Induced Replication: The Where, The Why, and The How

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12 December 2020

High speed of fork progression induces DNA replication stress and genomic instability

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12 December 2020

Histone H2A-H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin

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12 December 2020

The helicase Pif1 functions in the template switching pathway of DNA damage bypass

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12 December 2020

R-loop generation during transcription: Formation, processing and cellular outcomes

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12 December 2020

The Mcm2-Ctf4-Polα Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands

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12 December 2020

Pif1 is essential for efficient replisome progression through lagging strand G-quadruplex DNA secondary structures

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12 December 2020

Dna2 processes behind the fork long ssDNA flaps generated by Pif1 and replication-dependent strand displacement

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12 December 2020

Mechanism of Bidirectional Leading-Strand Synthesis Establishment at Eukaryotic DNA Replication Origins

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12 December 2020

PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification

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12 December 2020

Processing of eukaryotic Okazaki fragments by redundant nucleases can be uncoupled from ongoing DNA replication in vivo

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12 December 2020

Control of Eukaryotic DNA Replication Initiation-Mechanisms to Ensure Smooth Transitions

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12 December 2020