Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial (Q62587898)

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scientific article published on 22 September 2008

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English	Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial	scientific article published on 22 September 2008

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14 January 2020

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial (English)

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14 January 2020

type-1 diabetes

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14 January 2020

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Riitta Veijola

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Kirsti Näntö-Salonen

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14 January 2020

Antti Kupila

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Satu Simell

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14 January 2020

Heli Siljander

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14 January 2020

Tiina Salonsaari

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14 January 2020

Anne Hekkala

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14 January 2020

Sari Korhonen

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14 January 2020

Risto Erkkola

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14 January 2020

Jukka I Sipilä

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14 January 2020

Lotta Haavisto

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14 January 2020

Marja Siltala

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14 January 2020

Juhani Tuominen

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14 January 2020

Jari Hakalax

13

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14 January 2020

Jorma Ilonen

15

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14 January 2020

Tuula Simell

17

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14 January 2020

Olli Simell

19

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14 January 2020

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22 September 2008

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14 January 2020

1 reference

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14 January 2020

372

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14 January 2020

9651

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14 January 2020

1746-1755

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14 January 2020

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Environmental triggers and determinants of type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

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Metabolically inactive insulin analog prevents type I diabetes in prediabetic NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

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Insulin treatment in patients with type 1 diabetes induces upregulation of regulatory T-cell markers in peripheral blood mononuclear cells stimulated with insulin in vitro

1 reference

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7 January 2021

based on heuristic

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Immunological and metabolic effects of prophylactic insulin therapy in the NOD-scid/scid adoptive transfer model of IDDM

1 reference

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7 January 2021

based on heuristic

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Insulin prophylaxis in individuals at high risk of type I diabetes

1 reference

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7 January 2021

based on heuristic

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Effects of insulin in relatives of patients with type 1 diabetes mellitus

1 reference

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7 January 2021

based on heuristic

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Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

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Rapid HLA-DQB1 genotyping for four alleles in the assessment of risk for IDDM in the Finnish population. The Childhood Diabetes in Finland (DiMe) Study Group

1 reference

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7 January 2021

based on heuristic

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Population-based genetic screening for the estimation of Type 1 diabetes mellitus risk in Finland: selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic risk determines the emergence of diabetes-associated autoantibodies in young children

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

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First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes.

1 reference

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7 January 2021

based on heuristic

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Intranasally administered insulin intended for prevention of type 1 diabetes--a safety study in healthy adults

1 reference

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7 January 2021

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Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

1 reference

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7 January 2021

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Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

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7 January 2021

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Acoustic rhinometry: evaluation of nasal cavity geometry by acoustic reflection.

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7 January 2021

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Current issues in the treatment of human diseases by mucosal tolerance

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7 January 2021

based on heuristic

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Oral tolerance and TGF-beta-producing cells.

1 reference

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7 January 2021

based on heuristic

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Oral Administration of the Immunodominant B-chain of Insulin Reduces Diabetes in a Co-transfer Model of Diabetes in the NOD Mouse and is Associated with a Switch from Th1 to Th2 Cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Active suppression of diabetes after oral administration of insulin is determined by antigen dosage

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antigen delivery systems

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabète Insuline Orale group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

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Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes

1 reference

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7 January 2021

based on heuristic

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No effect of oral insulin on residual beta-cell function in recent-onset type I diabetes (the IMDIAB VII). IMDIAB Group.

1 reference

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7 January 2021

based on heuristic

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Potential risk of oral insulin with adjuvant for the prevention of Type I diabetes: a protocol effective in NOD mice may exacerbate disease in BB rats

1 reference

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7 January 2021

based on heuristic

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Theory and practice of nicotinamide trials in pre-type 1 diabetes

1 reference

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7 January 2021

based on heuristic

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HLA-DQB1-defined genetic susceptibility, beta cell autoimmunity, and metabolic characteristics in familial and nonfamilial insulin-dependent diabetes mellitus. Childhood Diabetes in Finland (DiMe) Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2961309-4

7 January 2021

based on heuristic

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Parental reactions to information about increased genetic risk of type 1 diabetes mellitus in infants

1 reference

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7 January 2021

based on heuristic

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Ketoacidosis at diagnosis of type 1 diabetes in children in northern Finland: temporal changes over 20 years

1 reference

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Immune intervention at diagnosis--should we treat children to preserve beta-cell function?

1 reference

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7 January 2021

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Identifiers

10.1016/S0140-6736(08)61309-4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18814906%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18814906%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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