Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway (Q61832628)

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5 January 2020

title

Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway (English)

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5 January 2020

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5 January 2020

Daming Zhu

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5 January 2020

Xueying Jiang

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5 January 2020

Xuan Wu

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5 January 2020

Feng Tian

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5 January 2020

Karen Mearow

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5 January 2020

Ann M Marini

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publication date

1 January 2004

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5 January 2020

published in

Neurotoxicity Research

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5 January 2020

volume

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issue

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5 January 2020

page(s)

281-289

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The role of depolarization in the survival and differentiation of cerebellar granule cells in culture

5 January 2020

cites work

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Protein kinase Czeta is a negative regulator of protein kinase B activity

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Activation of protein kinase C delays apoptosis of nerve growth factor-deprived rat sympathetic neurons through a Ca(2+)-influx dependent mechanism

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High K+ and IGF-1 protect cerebellar granule neurons via distinct signaling pathways

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Lithium inhibits caspase 3 activation and dephosphorylation of PKB and GSK3 induced by K+ deprivation in cerebellar granule cells

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Akt-dependent potentiation of L channels by insulin-like growth factor-1 is required for neuronal survival

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Neuronal necrosis inhibition by insulin through protein kinase C activation

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Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway

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Effects of depolarization and NMDA antagonists on the role survival of cerebellar granule cells: a pivotal role for protein kinase C isoforms.

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Inhibition of protein kinase C prevents Purkinje cell death but does not affect axonal regeneration.

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The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

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Different protein kinase C isoforms determine growth factor specificity in neuronal cells

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Attenuation of cell death mediated by membrane depolarization different from that by exogenous BDNF in cultured mouse cerebellar granule cells

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Nitric oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through cGMP-dependent PI3 kinase/Akt activation

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Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways

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N-methyl-D-aspartate receptor-mediated neuroprotection in cerebellar granule cells requires new RNA and protein synthesis

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Downregulating PKC delta provides a PI3K/Akt-independent survival signal that overcomes apoptotic signals generated by c-Src overexpression

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trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

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The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway.

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12 December 2020

Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway

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12 December 2020

Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons

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12 December 2020

Effect of depolarization on the maturation of cerebellar granule cells in culture

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12 December 2020

Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC.

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12 December 2020

Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action.

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Controlling calcium entry.

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12 December 2020

Activation of a PKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells

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12 December 2020

Synthetic lipid products of PI3-kinase which are added to culture medium prevent low K+-induced apoptosis of cerebellar granule neurons via Akt kinase activation

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12 December 2020

Distinct phosphorylation patterns underlie Akt activation by different survival factors in neurons

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12 December 2020

N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture

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12 December 2020

Protein kinase C--a question of specificity

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Brain-derived neurotrophic factor protection of cortical neurons from serum withdrawal-induced apoptosis is inhibited by cAMP.

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12 December 2020

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Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

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12 December 2020

Inhibition of insulin-induced activation of Akt by a kinase-deficient mutant of the epsilon isozyme of protein kinase C

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12 December 2020

Involvement of phosphatidylinositol-3 kinase in prevention of low K+-induced apoptosis of cerebellar granule neurons

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12 December 2020

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

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12 December 2020

Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate

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12 December 2020