Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production (Q61197433)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278262%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production (English)

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20 February 2020

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Michiel van der Vlist

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20 February 2020

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20 February 2020

Irma van Die

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20 February 2020

Sonja I Gringhuis

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20 February 2020

Tanja M Kaptein

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20 February 2020

Brigitte A Wevers

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20 February 2020

Lianne E M Vriend

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20 February 2020

Marein A W P de Jong

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20 February 2020

Teunis B H Geijtenbeek

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20 February 2020

language of work or name

English

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publication date

3 October 2014

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20 February 2020

published in

Nature Communications

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20 February 2020

volume

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20 February 2020

issue

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page(s)

5074

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Diversity and dialogue in immunity to helminths.

20 February 2020

cites work

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The origins, function, and regulation of T follicular helper cells

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Unique maturation program of the IgE response in vivo

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Sequential class switching is required for the generation of high affinity IgE antibodies

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Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.

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An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

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The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response

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ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

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IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

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Bcl6 mediates the development of T follicular helper cells

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Development and characterization of IL-21-producing CD4+ T cells

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In vivo regulation of Bcl6 and T follicular helper cell development

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

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7 January 2021

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

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7 January 2021

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

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7 January 2021

Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation

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7 January 2021

Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion

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7 January 2021

The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells

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7 January 2021

PD-1(HIGH) Follicular CD4 T Helper Cell Subsets Residing in Lymph Node Germinal Centers Correlate with B Cell Maturation and IgG Production in Rhesus Macaques

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Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

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Glycan gimmickry by parasitic helminths: a strategy for modulating the host immune response?

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7 January 2021

The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.

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7 January 2021

Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity

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7 January 2021

IκB kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses

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7 January 2021

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7 January 2021

Tracking STAT nuclear traffic

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7 January 2021

Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells

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7 January 2021

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.

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7 January 2021

Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process

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Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology

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7 January 2021

Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanism

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7 January 2021

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7 January 2021

T follicular helper cells differentiate from Th2 cells in response to helminth antigens

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7 January 2021

Soluble helminth products suppress clinical signs in murine experimental autoimmune encephalomyelitis and differentially modulate human dendritic cell activation.

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Identifiers

DOI

10.1038/NCOMMS6074

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278262%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 February 2020

ADS bibcode

2014NatCo...5.5074G

0 references

1026271830

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1 reference

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