Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy (Q61053669)

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scientific article published on 17 January 2019

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English	Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy	scientific article published on 17 January 2019

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scholarly article

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

title

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy (English)

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

main subject

Hepatitis C virus non-structural 5a protein family

0 references

antiviral drug

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Flavivirus

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post-translational protein modification

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Zika virus

1 reference

based on heuristic

inferred from title

author

Zheng Zhu

series ordinal

1

1 reference

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

Hin Chu

series ordinal

2

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Jie Zhou

series ordinal

9

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

K H Kok

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12

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Jasper Fuk-Woo Chan

series ordinal

14

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Cyril Chik-Yan Yip

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7

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Cyril Chik-Yan Yip

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Europe PubMed Central

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6359730

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19 April 2020

Yuen Kwok-yung

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13

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Kwok-Yung Yuen

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6359730

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19 April 2020

author name string

Lei Wen

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3

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Europe PubMed Central

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6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Shuofeng Yuan

series ordinal

4

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Europe PubMed Central

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6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Kenn Ka-Heng Chik

series ordinal

5

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Europe PubMed Central

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6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Terrence Tsz-Tai Yuen

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6

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Dong Wang

series ordinal

8

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Feifei Yin

series ordinal

10

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

Dong-Yan Jin

series ordinal

11

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

language of work or name

English

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publication date

17 January 2019

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

published in

International Journal of Molecular Sciences

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Europe PubMed Central

PMC publication ID

6359730

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

volume

20

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Europe PubMed Central

PMC publication ID

6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

issue

2

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Europe PubMed Central

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6359730

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

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19 April 2020

page(s)

392

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copyright license

Creative Commons Attribution 4.0 International

start time

17 January 2019

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stated in

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction

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reference URL

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Sequence logos: a new way to display consensus sequences

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reference URL

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SUMO--nonclassical ubiquitin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

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SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

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DNA viruses and viral proteins that interact with PML nuclear bodies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

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WebLogo: A Sequence Logo Generator

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein modification by SUMO

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viruses and sumoylation: recent highlights

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Development of Multiplex Real-Time Reverse Transcriptase PCR Assays for Detecting Eight Medically Important Flaviviruses in Mosquitoes

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PubMed

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12 December 2020

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SUMO junction-what's your function? New insights through SUMO-interacting motifs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

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Sumoylation regulates diverse biological processes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

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Concepts in sumoylation: a decade on

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PubMed

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12 December 2020

based on heuristic

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Papillomaviruses and the host SUMOylation system

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

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Zika Virus Outbreak on Yap Island, Federated States of Micronesia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

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Modification of small hepatitis delta virus antigen by SUMO protein

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12 December 2020

based on heuristic

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The SUMOylation of Matrix Protein M1 Modulates the Assembly and Morphogenesis of Influenza A Virus

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PubMed

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12 December 2020

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Insights into High Affinity Small Ubiquitin-like Modifier (SUMO) Recognition by SUMO-interacting Motifs (SIMs) Revealed by a Combination of NMR and Peptide Array Analysis

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Function and regulation of SUMO proteases

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12 December 2020

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An electrophoretic mobility shift assay identifies a mechanistically unique inhibitor of protein sumoylation

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12 December 2020

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SUMOylation of nonstructural 5A protein regulates hepatitis C virus replication

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PubMed

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Universal single-probe RT-PCR assay for diagnosis of dengue virus infections

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SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription

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Suppression of type I and type III IFN signalling by NSs protein of severe fever with thrombocytopenia syndrome virus through inhibition of STAT1 phosphorylation and activation

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The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes.

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https://pubmed.ncbi.nlm.nih.gov/30658479

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Evolution of SUMO Function and Chain Formation in Insects.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

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SUMO Modification Stabilizes Dengue Virus Nonstructural Protein 5 To Support Virus Replication

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

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Zika fever and congenital Zika syndrome: An unexpected emerging arboviral disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

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Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zika Virus

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The implication of SUMO in intrinsic and innate immunity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real time PCR assay for detection of all known lineages of West Nile virus

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https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

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Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs

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https://pubmed.ncbi.nlm.nih.gov/30658479

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Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Effectively Treated by Recombinant Type I Interferons

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12 December 2020

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Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5’-untranslated region of Zika virus

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30658479

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of the Zika virus full-length NS5 protein

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PubMed

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Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein

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PubMed

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Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo

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reference URL

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The immunopathology of dengue and Zika virus infections

1 reference

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inferred from PubMed ID database lookup

Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function

1 reference

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inferred from PubMed ID database lookup

Glutathionylation of dengue and Zika NS5 proteins affects guanylyltransferase and RNA dependent RNA polymerase activities.

1 reference

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reference URL

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Immunization with a Novel Human type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models.

1 reference

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retrieved

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The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy

1 reference

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reference URL

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retrieved

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SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30658479

retrieved

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based on heuristic

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Identifiers

DOI

10.3390/IJMS20020392

1 reference

stated in

Europe PubMed Central

PMC publication ID

6359730

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

PMC publication ID

6359730

1 reference

stated in

Europe PubMed Central

PMC publication ID

6359730

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

PubMed publication ID

30658479

1 reference

stated in

Europe PubMed Central

PMC publication ID

6359730

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658479%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 April 2020

 

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