Mitochondrial Quality Control Mechanisms and the PHB (Prohibitin) Complex (Q60926937)

12 December 2020

Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria

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12 December 2020

The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins

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12 December 2020

C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane

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12 December 2020

Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.

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12 December 2020

The phagosome proteome: insight into phagosome functions

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12 December 2020

Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence

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12 December 2020

Shy1p occurs in a high molecular weight complex and is required for efficient assembly of cytochrome c oxidase in yeast

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12 December 2020

The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease

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12 December 2020

A structure for the yeast prohibitin complex: Structure prediction and evidence from chemical crosslinking and mass spectrometry.

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12 December 2020

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

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12 December 2020

Rates of behavior and aging specified by mitochondrial function during development

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12 December 2020

Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine biosynthetic machinery with the prohibitin complex of Saccharomyces cerevisiae

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12 December 2020

The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans

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12 December 2020

The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells

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12 December 2020

Protein components of mitochondrial DNA nucleoids in higher eukaryotes

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12 December 2020

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

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12 December 2020

Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes

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12 December 2020

Mitochondria, oxidants, and aging

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12 December 2020

Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

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12 December 2020

Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response

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12 December 2020

Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane.

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12 December 2020

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

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12 December 2020

Prohibitins interact genetically with Atp23, a novel processing peptidase and chaperone for the F1Fo-ATP synthase.

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12 December 2020

Molecular modeling of prohibitin domains

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12 December 2020

The SPFH domain-containing proteins: more than lipid raft markers

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12 December 2020

Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans

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12 December 2020

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans

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12 December 2020

Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

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12 December 2020

Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids

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12 December 2020

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

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12 December 2020

The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals

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12 December 2020

Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis.

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12 December 2020

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

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12 December 2020

The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria

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12 December 2020

An ER-mitochondria tethering complex revealed by a synthetic biology screen

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12 December 2020

The BCL-2-like protein CED-9 of C. elegans promotes FZO-1/Mfn1,2- and EAT-3/Opa1-dependent mitochondrial fusion

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12 December 2020

Dual functions of Mss51 couple synthesis of Cox1 to assembly of cytochrome c oxidase in Saccharomyces cerevisiae mitochondria

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12 December 2020

Prohibitin and mitochondrial biology

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12 December 2020

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans

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12 December 2020

The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans

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12 December 2020

Histone methyl transferases and demethylases; can they link metabolism and transcription?

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12 December 2020

Sphingosine‐1‐phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

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12 December 2020

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

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12 December 2020

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12 December 2020

Taking a "good" look at free radicals in the aging process

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12 December 2020

Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos

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12 December 2020

Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission

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12 December 2020

Identification of core components and transient interactors of the peroxisomal importomer by dual-track stable isotope labeling with amino acids in cell culture analysis

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12 December 2020

Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease

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12 December 2020

Role of MINOS in mitochondrial membrane architecture and biogenesis.

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12 December 2020

Barriers to male transmission of mitochondrial DNA in sperm development

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12 December 2020

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

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12 December 2020

Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses

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12 December 2020

C. elegans detects pathogen-induced translational inhibition to activate immune signaling

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12 December 2020

Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

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12 December 2020

Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

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12 December 2020

Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition

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12 December 2020

Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration

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12 December 2020

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

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12 December 2020

Prohibitin ligands in cell death and survival: mode of action and therapeutic potential

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12 December 2020

Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure

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12 December 2020

Mitonuclear protein imbalance as a conserved longevity mechanism

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12 December 2020

The hallmarks of aging

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12 December 2020

Molecular mechanisms underlying genotype-dependent responses to dietary restriction.

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12 December 2020

The ire-1 ER stress-response pathway is required for normal secretory-protein metabolism in C. elegans

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12 December 2020

Mitochondrial lipid trafficking

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12 December 2020

Muscle mitohormesis promotes longevity via systemic repression of insulin signaling

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12 December 2020

The protein import machinery of mitochondria-a regulatory hub in metabolism, stress, and disease

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12 December 2020

Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans

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12 December 2020

Caenorhabditis elegans pathways that surveil and defend mitochondria

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12 December 2020

Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

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12 December 2020

Paternal mitochondrial destruction after fertilization is mediated by a common endocytic and autophagic pathway in Drosophila.

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12 December 2020

DNAJC19, a mitochondrial cochaperone associated with cardiomyopathy, forms a complex with prohibitins to regulate cardiolipin remodeling

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12 December 2020

A trifluorinated thiazoline scaffold leading to pro-apoptotic agents targeting prohibitins

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12 December 2020

Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans

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12 December 2020

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

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12 December 2020

Mitochondrial dynamics and mitochondrial quality control

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12 December 2020

The mitochondrial unfolded protein response—synchronizing genomes

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12 December 2020

Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa

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12 December 2020

Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt).

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12 December 2020

Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function.

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12 December 2020

UPR(mt)-mediated cytoprotection and organismal aging

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12 December 2020

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

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12 December 2020

Ca(2+) homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling

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12 December 2020

Analysis of the effect of the mitochondrial prohibitin complex, a context-dependent modulator of longevity, on the C. elegans metabolome.

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12 December 2020

Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes

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12 December 2020

Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans

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12 December 2020

A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death

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12 December 2020

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol.

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12 December 2020

Ubiquitin-Dependent And Independent Signals In Selective Autophagy

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12 December 2020

Human Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane Structure

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12 December 2020

Interaction of MDM33 with mitochondrial inner membrane homeostasis pathways in yeast

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12 December 2020

Mitonuclear communication in homeostasis and stress

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12 December 2020

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

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12 December 2020

Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR(mt).

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12 December 2020

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

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12 December 2020

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

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12 December 2020

Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

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12 December 2020

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells

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12 December 2020

The Mitochondria-Regulated Immune Pathway Activated in the C. elegans Intestine Is Neuroprotective.

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12 December 2020

Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response.

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12 December 2020

Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis.

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12 December 2020

Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response

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12 December 2020

Prohibitin confers cytoprotection against ISO-induced hypertrophy in H9c2 cells via attenuation of oxidative stress and modulation of Akt/Gsk-3β signaling.

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12 December 2020

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites.

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12 December 2020

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor

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12 December 2020

Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes.

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12 December 2020

Mitochondrial metabolites: undercover signalling molecules

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12 December 2020

Prohibitin - At the crossroads of obesity-linked diabetes and cancer.

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12 December 2020

Mitochondrial adventures at the organelle society

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12 December 2020

Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death

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12 December 2020

Mitochondrial prohibitin and its ubiquitination during spermatogenesis of the swimming crab Charybdis japonica

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12 December 2020

Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.

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12 December 2020

DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy

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12 December 2020

Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways.

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12 December 2020

Cryo-EM Structure of the TOM Core Complex from Neurospora crassa

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12 December 2020

ATAD3 proteins: brokers of a mitochondria-endoplasmic reticulum connection in mammalian cells

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12 December 2020

Prohibitin: A new player in immunometabolism and in linking obesity and inflammation with cancer.

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12 December 2020

Prohibitin-mediated mitochondrial ubiquitination during spermiogenesis in Chinese mitten crab Eriocheir sinensis

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12 December 2020

PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol

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12 December 2020

The expression pattern and potential functions of PHB in the spermiogenesis of Phascolosoma esculenta.

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12 December 2020

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.

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12 December 2020

Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans.

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12 December 2020

Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis

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12 December 2020

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels

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12 December 2020

The different axes of the mammalian mitochondrial unfolded protein response

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12 December 2020

The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling

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12 December 2020

Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress

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12 December 2020

USP14 inhibition corrects an model of impaired mitophagy

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12 December 2020