Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review (Q60917030)

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scientific article published on 08 January 2019

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English	Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review	scientific article published on 08 January 2019

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scholarly article

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Europe PubMed Central

PMC publication ID

6337480

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

review article

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PubMed publication ID

30626121

title

Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review (English)

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PMC publication ID

6337480

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

main subject

hepatocellular carcinoma

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stated in

PubMed

retrieved

21 December 2019

liver neoplasm

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PubMed

retrieved

21 December 2019

tumor biomarker

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stated in

PubMed

retrieved

7 August 2019

laminin

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PubMed

retrieved

21 December 2019

biomarker

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based on heuristic

inferred from title

author

Hiroshi Yasuda

series ordinal

1

1 reference

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Europe PubMed Central

PMC publication ID

6337480

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

Hirofumi Kiyokawa

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3

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Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

author name string

Masatoshi Nakagawa

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2

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Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

Eisaku Yoshida

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4

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PMC publication ID

6337480

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

Toru Yoshimura

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5

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6337480

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

Naohiko Koshikawa

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6

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6337480

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18 April 2020

Fumio Itoh

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7

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6337480

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

Motoharu Seiki

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8

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Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

Hiroshi Yasuda

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1

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Hirofumi Kiyokawa

series ordinal

3

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language of work or name

English

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publication date

8 January 2019

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PubMed Central

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19 June 2019

stated in

PubMed Central

retrieved

7 August 2019

stated in

PubMed Central

retrieved

15 December 2019

stated in

PubMed Central

retrieved

21 December 2019

stated in

Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

January 2019

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full work available at URL

https://www.mdpi.com/1422-0067/20/1/226

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published in

International Journal of Molecular Sciences

5 references

stated in

PubMed Central

retrieved

19 June 2019

stated in

PubMed Central

retrieved

7 August 2019

stated in

PubMed Central

retrieved

15 December 2019

stated in

PubMed Central

retrieved

21 December 2019

stated in

Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

volume

20

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Europe PubMed Central

PMC publication ID

6337480

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

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18 April 2020

issue

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

page(s)

226

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copyright license

Creative Commons Attribution

4 references

stated in

PubMed Central

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19 June 2019

stated in

PubMed Central

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7 August 2019

stated in

PubMed Central

retrieved

15 December 2019

stated in

PubMed Central

retrieved

21 December 2019

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copyrighted

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Overexpression of laminin gamma2 chain monomer in invading gastric carcinoma cells

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Form and function: the laminin family of heterotrimers

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Expression of the gamma(2) chain of laminin-5 at the invasive front is associated with recurrence and poor prognosis in human esophageal squamous cell carcinoma

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Expression of laminin-5-gamma-2 chain in intraductal papillary-mucinous and invasive ductal tumors of the pancreas

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The LG3 module of laminin-5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading, and migration

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Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin

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Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas

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Cytoplasmic expression of laminin gamma2 chain correlates with postoperative hepatic metastasis and poor prognosis in patients with pancreatic ductal adenocarcinoma

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Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution.

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Epigenetic inactivation of laminin-5-encoding genes in lung cancers.

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Laminin-5 chains are expressed differentially in metastatic and nonmetastatic hepatocellular carcinoma

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Aberrant promoter methylation and silencing of laminin-5-encoding genes in breast carcinoma

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Aberrant promoter methylation of laminin-5-encoding genes in prostate cancers and its relationship to clinicopathological features

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Molecular detection of noninvasive and invasive bladder tumor tissues and exfoliated cells by aberrant promoter methylation of laminin-5 encoding genes

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Randomized controlled trial of screening for hepatocellular carcinoma

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Analysis of DNA copy number aberrations in hepatitis C virus-associated hepatocellular carcinomas by conventional CGH and array CGH.

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12 December 2020

based on heuristic

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Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.

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https://pubmed.ncbi.nlm.nih.gov/30626121

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin gamma2-chain fragment circulating level increases in patients with metastatic pancreatic ductal cell adenocarcinomas

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Laminin-5 (laminin-332): Unique biological activity and role in tumor growth and invasion

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The short arm of laminin gamma2 chain of laminin-5 (laminin-332) binds syndecan-1 and regulates cellular adhesion and migration by suppressing phosphorylation of integrin beta4 chain

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Development of a new tracking tool for the human monomeric laminin-gamma 2 chain in vitro and in vivo

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12 December 2020

based on heuristic

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Serum concentrations of laminin gamma2 fragments in patients with head and neck squamous cell carcinoma

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based on heuristic

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Role of serum prothrombin induced by vitamin K absence or antagonist-II in the early detection of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

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Laminin gamma2 mediates Wnt5a-induced invasion of gastric cancer cells

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Significance of alpha-fetoprotein and des-gamma-carboxy prothrombin in patients with hepatocellular carcinoma undergoing hepatectomy

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12 December 2020

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Defining the role of laminin-332 in carcinoma

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https://pubmed.ncbi.nlm.nih.gov/30626121

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of beta3/gamma2 chains of laminin-5 and MMP7 in biliary cancer.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30626121

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin gamma2 fragments are increased in the circulation of patients with early phase acute lung injury

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postoperative serum alpha-fetoprotein level is a useful predictor of recurrence after hepatectomy for hepatocellular carcinoma

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Management of hepatocellular carcinoma: An update

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin 332 processing impacts cellular behavior

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin, gamma 2 (LAMC2): a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnostic accuracy of des-gamma-carboxy prothrombin versus α-fetoprotein for hepatocellular carcinoma: A systematic review

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of laminin 332 on motility and invasion in bladder cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of abdominal ultrasonography mass screening for hepatocellular carcinoma in Taiwan

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin-5γ-2 (LAMC2) is highly expressed in anaplastic thyroid carcinoma and is associated with tumor progression, migration, and invasion by modulating signaling of EGFR.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the tissue microenvironment as a therapeutic target in hepatocellular carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Migration of breast cancer cell lines in response to pulmonary laminin 332.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum monomeric laminin-γ2 as a novel biomarker for hepatocellular carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a fully automated chemiluminescence immunoassay for urine monomeric laminin-γ2 as a promising diagnostic tool of non-muscle invasive bladder cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of α3, β3 and γ2 chains of laminin-332 is associated with poor prognosis in pancreatic ductal adenocarcinoma.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30626121

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.3390/IJMS20010226

1 reference

stated in

Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

PMC publication ID

6337480

1 reference

stated in

Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

PubMed publication ID

30626121

1 reference

stated in

Europe PubMed Central

PMC publication ID

6337480

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30626121%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 April 2020

 

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