The Role of Placental Inflammasomes in Linking the Adverse Effects of Maternal Obesity on Fetal Development (Q60539255)

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Fetuses of obese mothers develop insulin resistance in utero

31 March 2020

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Impact of maternal obesity on offspring obesity and cardiometabolic disease risk

31 March 2020

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Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years

31 March 2020

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Inflammation and metabolic disorders

31 March 2020

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Inflammatory links between obesity and metabolic disease

31 March 2020

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Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation

31 March 2020

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https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Increasing maternal body mass index is associated with systemic inflammation in the mother and the activation of distinct placental inflammatory pathways.

31 March 2020

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Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta

31 March 2020

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https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Placental structure and inflammation in pregnancies associated with obesity.

31 March 2020

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Maternal obesity is associated with a lipotoxic placental environment

31 March 2020

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Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies.

31 March 2020

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Impaired mitochondrial function in human placenta with increased maternal adiposity

31 March 2020

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Maternal obesity alters feto-placental cytochrome P4501A1 activity

31 March 2020

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Maternal obesity and its effect on placental cell turnover.

31 March 2020

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Chorionic plate arterial function is altered in maternal obesity.

31 March 2020

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Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillbirth in a nonhuman primate model of excess nutrition

31 March 2020

1 reference

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Placental oleic acid uptake is lower in male offspring of obese women

31 March 2020

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Reduced placental taurine transporter (TauT) activity in pregnancies complicated by pre-eclampsia and maternal obesity

31 March 2020

1 reference

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Protection from obesity-induced insulin resistance in mice lacking TNF-α function

31 March 2020

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The association between TNF-α and insulin resistance in euglycemic women

31 March 2020

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https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

31 March 2020

1 reference

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Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways.

31 March 2020

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Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses

31 March 2020

1 reference

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Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition

31 March 2020

1 reference

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Endogenous ligands of Toll-like receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity.

31 March 2020

1 reference

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Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

NF-κB, inflammation, and metabolic disease.

31 March 2020

1 reference

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The Role of JNK Proteins in Metabolism

31 March 2020

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Multiparity leads to obesity and inflammation in mothers and obesity in male offspring

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity

31 March 2020

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Cellular inhibitors of apoptosis (cIAP) 1 and 2 are increased in placenta from obese pregnant women.

31 March 2020

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Maternal obesity and risk of preterm delivery

31 March 2020

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Hyperglycemia and adverse pregnancy outcomes

31 March 2020

1 reference

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Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Uteroplacental Circulation and Fetal Vascular Function and Development

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2

31 March 2020

1 reference

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Effect of IL-6 and TNF-α on fatty acid uptake in cultured human primary trophoblast cells

31 March 2020

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Leptin affects system A amino acid transport activity in the human placenta: evidence for STAT3 dependent mechanisms.

31 March 2020

1 reference

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Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments.

31 March 2020

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Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells

31 March 2020

1 reference

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Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts.

31 March 2020

1 reference

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Inhibition of amino acid transport system a by interleukin-1beta in trophoblasts

31 March 2020

1 reference

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Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport

31 March 2020

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Bacterial LPS differently modulates inflammasome gene expression and IL-1β secretion in trophoblast cells, decidual stromal cells, and decidual endothelial cells

31 March 2020

1 reference

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The interleukin-1 system in gestational tissues at term: Effect of labour

31 March 2020

1 reference

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Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition

31 March 2020

1 reference

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Regulation of apoptosis and innate immune stimuli in inflammation-induced preterm labor

31 March 2020

1 reference

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Uric acid induces trophoblast IL-1β production via the inflammasome: implications for the pathogenesis of preeclampsia

31 March 2020

1 reference

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A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast.

31 March 2020

1 reference

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Trophoblast debris extruded from preeclamptic placentae activates endothelial cells: a mechanism by which the placenta communicates with the maternal endothelium

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Nod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Interleukin-1beta induces the expression of insulin-like growth factor binding protein-1 during decidualization in the primate

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

The regulation of progesterone and hCG production from placental cells by interleukin-1β

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Interleukin-1beta-induced expression of IL-6 and production of human chorionic gonadotropin in human trophoblast cells via nuclear factor-kappaB activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Regulation of activin-A production by human amnion, decidua and placenta in vitro by pro-inflammatory cytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

IL-1β is a Better Inducer of Apoptosis in Human Fetal Membranes than IL-6

31 March 2020

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Inflammasomes: too big to miss

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

The effect of pre-existing maternal obesity and diabetes on placental mitochondrial content and electron transport chain activity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Differences in maternal circulating fatty acid composition and dietary fat intake in women with gestational diabetes mellitus or mild gestational hyperglycemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primates

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Inflammasome-mediated secretion of IL-1β in human monocytes through TLR2 activation; modulation by dietary fatty acids.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-κB activation and enhancing autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Placental Amino Acid Uptake in Normal and Complicated Pregnancies

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Altered activity of the system A amino acid transporter in microvillous membrane vesicles from placentas of macrosomic babies born to diabetic women

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Placental infiltration of inflammatory markers in gestational diabetic women

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Gestational diabetes induces placental genes for chronic stress and inflammatory pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Diabetes during pregnancy influences Hofbauer cells, a subtype of placental macrophages, to acquire a pro-inflammatory phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Assessment of the number and function of macrophages in the placenta of gestational diabetes mellitus patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

A comparison of glyburide and insulin in women with gestational diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

The use of glyburide in the management of gestational diabetes mellitus: a meta-analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6

Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-16853-1_6