Mixing lipids to manipulate the ionization status of lipid nanoparticles for specific tissue targeting (Q60304254)

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English	Mixing lipids to manipulate the ionization status of lipid nanoparticles for specific tissue targeting	No description defined

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instance of

scholarly article

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title

Mixing lipids to manipulate the ionization status of lipid nanoparticles for specific tissue targeting (English)

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main subject

biophysics

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bioengineering

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drug discovery

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nanoparticle

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based on heuristic

inferred from title

author

Nour Shobaki

object named as

Nour Shobaki

series ordinal

1

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author name string

Yusuke Sato

series ordinal

2

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Hideyoshi Harashima

series ordinal

3

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language of work or name

English

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publication date

2018

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number of pages

16

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based on heuristic

inferred from page(s)

published in

International Journal of Nanomedicine

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volume

13

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page(s)

8395-8410

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copyright license

Creative Commons Attribution-NonCommercial 3.0 Unported

start time

1 December 2018

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stated in

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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stated in

Europe PubMed Central

retrieved

11 June 2022

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6294068/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

Filtration of chylomicrons by the liver may influence cholesterol metabolism and atherosclerosis

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Liposomes and local hyperthermia: selective delivery of methotrexate to heated tumors

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Scavenger functions of the liver endothelial cell

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Tumoritropic and lymphotropic principles of macromolecular drugs

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A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

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reference URL

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12 December 2020

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An ultrastructural characterization of the endothelial cell in the rat liver sinusoid under normal and various experimental conditions, as a contribution to the distinction between endothelial and Kupffer cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

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inferred from PubMed ID database lookup

Formation of cholesteryl ester-rich particulate lipid during metabolism of chylomicrons

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reference URL

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12 December 2020

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An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids

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Immunotoxins: A New Approach to Cancer Therapy

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Modulation of membrane fusion by asymmetric transbilayer distributions of amino lipids

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12 December 2020

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Defenestration of the sinusoidal endothelial cell in a rat model of cirrhosis

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Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids

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Platelet-endothelial cell adhesion molecule-1 gene expression in liver sinusoidal endothelial cells during liver injury and repair

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Massive and selective delivery of lipid-coated cationic lipoplexes of oligonucleotides targeted in vivo to hepatic endothelial cells

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12 December 2020

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inferred from PubMed ID database lookup

Capillarization of hepatic sinusoids in man

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PubMed

reference URL

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12 December 2020

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Targeted gene delivery to sinusoidal endothelial cells: DNA nanoassociate bearing hyaluronan-glycocalyx

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PubMed

reference URL

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12 December 2020

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3H dendrimer nanoparticle organ/tumor distribution.

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reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

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12 December 2020

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inferred from PubMed ID database lookup

Optimized targeting of polyethylene glycol-stabilized anti-intercellular adhesion molecule 1 oligonucleotide/lipid particles to liver sinusoidal endothelial cells.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

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12 December 2020

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inferred from PubMed ID database lookup

The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence

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https://pubmed.ncbi.nlm.nih.gov/30587967

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12 December 2020

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inferred from PubMed ID database lookup

Factors affecting the clearance and biodistribution of polymeric nanoparticles.

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12 December 2020

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inferred from PubMed ID database lookup

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

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12 December 2020

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Physiology and pathophysiology of liver inflammation, damage and repair

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12 December 2020

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Active targeting schemes for nanoparticle systems in cancer therapeutics

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reference URL

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12 December 2020

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Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium.

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12 December 2020

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inferred from PubMed ID database lookup

Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute liver failure: mechanisms of immune-mediated liver injury

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Colon carcinoma cell interaction with liver sinusoidal endothelium inhibits organ-specific antitumor immunity through interleukin-1-induced mannose receptor in mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

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12 December 2020

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inferred from PubMed ID database lookup

Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: New targets for the treatment of portal hypertension?

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Update on the Role of Endothelial Lipase in High-Density Lipoprotein Metabolism, Reverse Cholesterol Transport, and Atherosclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionization behavior of amino lipids for siRNA delivery: determination of ionization constants, SAR, and the impact of lipid pKa on cationic lipid-biomembrane interactions

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Hepatic Lipase and Endothelial Lipase in High-Density Lipoprotein—Mediated Reverse Cholesterol Transport

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Development of an efficient short interference RNA (siRNA) delivery system with a new pH-sensitive cationic lipid]

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific gene delivery to liver sinusoidal and artery endothelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A liposomal delivery system that targets liver endothelial cells based on a new peptide motif present in the ApoB-100 sequence

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo therapeutic potential of Dicer-hunting siRNAs targeting infectious hepatitis C virus.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multifunctional envelope-type nano device for controlled intracellular trafficking and selective targeting in vivo.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancing siRNA delivery by employing lipid nanoparticles

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand density at the surface of a nanoparticle and different uptake mechanism: two important factors for successful siRNA delivery to liver endothelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid nanoparticles for short interfering RNA delivery

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid nanoparticle delivery systems for siRNA-based therapeutics

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Size-dependent specific targeting and efficient gene silencing in peritoneal macrophages using a pH-sensitive cationic liposomal siRNA carrier

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bridging small interfering RNA with giant therapeutic outcomes using nanometric liposomes

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Design of Ionizable Lipids To Overcome the Limiting Step of Endosomal Escape: Application in the Intracellular Delivery of mRNA, DNA, and siRNA.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

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Protein corona: a new approach for nanomedicine design

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30587967

retrieved

12 December 2020

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Identifiers

DOI

10.2147/IJN.S188016

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PMC publication ID

6294068

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PubMed publication ID

30587967

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