Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6. (Q64916187)

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scientific article published on 7 June 2019

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English	Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6.	scientific article published on 7 June 2019

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6556981

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30 June 2019

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Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6. (English)

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6556981

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Caroline Bull Melsom

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1

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6556981

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30 June 2019

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Marie-Victoire Cosson

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2

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6556981

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Øivind Ørstavik

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3

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6556981

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Ngai Chin Lai

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4

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6556981

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H Kirk Hammond

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5

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6556981

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Jan-Bjørn Osnes

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6

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6556981

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Tor Skomedal

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7

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6556981

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Viacheslav Nikolaev

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8

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6556981

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Finn Olav Levy

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9

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6556981

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Kurt Allen Krobert

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10

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6556981

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7 June 2019

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PLOS One

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6556981

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volume

14

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6556981

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30 June 2019

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6

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6556981

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30 June 2019

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e0218110

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6556981

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7 June 2019

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Quantification of signalling components and amplification in the beta-adrenergic-receptor-adenylate cyclase pathway in isolated adult rat ventricular myocytes

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Regulation of adenylyl cyclase by protein kinase A

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12 December 2020

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Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes

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Differential activation of adenylyl cyclase by protein kinase C isoenzymes

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12 December 2020

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Ca(2+)-inhibited adenylyl cyclase in cardiac tissue

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Protein kinase C alters the responsiveness of adenylyl cyclases to G protein alpha and betagamma subunits

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Comparison between alpha-1 adrenoceptor-mediated and beta adrenoceptor-mediated inotropic components elicited by norepinephrine in failing human ventricular muscle

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Protein kinase C inhibits adenylyl cyclase type VI activity during desensitization of the A2a-adenosine receptor-mediated cAMP response

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12 December 2020

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Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Gα s stimulation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31173603

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1 Mammalian adenylyl cyclases

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Inverse agonists and neutral antagonists of recombinant human A1 adenosine receptors stably expressed in Chinese hamster ovary cells

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Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes

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12 December 2020

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Inhibition by calcium of mammalian adenylyl cyclases

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12 December 2020

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Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase

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Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase

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Heart failure -- a challenge to our current concepts of excitation-contraction coupling

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12 December 2020

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Molecular and cellular requirements for the regulation of adenylate cyclases by calcium

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12 December 2020

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An important functional role of the N terminus domain of type VI adenylyl cyclase in Galphai-mediated inhibition

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Modeling of Galpha(s) and Galpha(i) regulation of human type V and VI adenylyl cyclase

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Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart

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Regulatory properties of adenylate cyclases type 5 and 6: A progress report

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12 December 2020

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Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains

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New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy

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Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling

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PubMed

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12 December 2020

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N terminus of type 5 adenylyl cyclase scaffolds Gs heterotrimer

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PubMed

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12 December 2020

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31173603

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12 December 2020

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The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31173603

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12 December 2020

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inferred from PubMed ID database lookup

Adenylyl cyclase subtype-specific compartmentalization: differential regulation of L-type Ca2+ current in ventricular myocytes

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gi proteins regulate adenylyl cyclase activity independent of receptor activation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31173603

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12 December 2020

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inferred from PubMed ID database lookup

Non-classical regulation of β1- and β 2-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein Gi

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PubMed

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12 December 2020

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inferred from PubMed ID database lookup

Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy

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PubMed

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12 December 2020

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In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β1-adrenoceptor-mediated inotropic response

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31173603

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12 December 2020

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Identifiers

DOI

10.1371/JOURNAL.PONE.0218110

1 reference

stated in

Europe PubMed Central

PMC publication ID

6556981

retrieved

30 June 2019

reference URL

http://europepmc.org/abstract/PMC/6556981

PMC publication ID

6556981

1 reference

stated in

Europe PubMed Central

PMC publication ID

6556981

retrieved

30 June 2019

reference URL

http://europepmc.org/abstract/PMC/6556981

PubMed publication ID

31173603

1 reference

stated in

Europe PubMed Central

PMC publication ID

6556981

retrieved

30 June 2019

reference URL

http://europepmc.org/abstract/PMC/6556981

 

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