A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study (Q64071609)

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scientific article published on 05 April 2019

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English	A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study	scientific article published on 05 April 2019

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Europe PubMed Central

PMC publication ID

6459887

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31024619%20AND%20SRC:MED&resulttype=core&format=json

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23 April 2020

title

A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study (English)

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PMC publication ID

6459887

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23 April 2020

main subject

Mendelian randomization

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author

Liang Cheng

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3

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PMC publication ID

6459887

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23 April 2020

author name string

He Zhuang

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1

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PMC publication ID

6459887

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23 April 2020

Junwei Han

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2

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6459887

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23 April 2020

Shu-Lin Liu

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4

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PMC publication ID

6459887

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23 April 2020

language of work or name

English

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publication date

5 April 2019

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6459887

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23 April 2020

published in

Frontiers in Genetics

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PMC publication ID

6459887

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23 April 2020

volume

10

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23 April 2020

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295

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23 April 2020

copyright license

Creative Commons Attribution 4.0 International

start time

5 April 2019

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cites work

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Propionibacterium acnes treatment diminishes CD4+ NK1.1+ T cells but induces type I T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells

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Mycobacterium bovis BCG vaccination augments interleukin-8 mRNA expression and protein production in guinea pig alveolar macrophages infected with Mycobacterium tuberculosis

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Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans

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High serum interleukin-18 concentrations in patients with coronary artery disease and type 2 diabetes mellitus

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Interleukin-1-receptor antagonist in type 2 diabetes mellitus

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MENDEL'S LAW OF HEREDITY.

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Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.

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Circulating IL-18 and the risk of type 2 diabetes in women

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Prebiotic oligosaccharides reduce proinflammatory cytokines in intestinal Caco-2 cells via activation of PPARγ and peptidoglycan recognition protein 3.

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Five years of GWAS discovery

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Interleukin-1 (IL-1) family of cytokines: role in type 2 diabetes

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Imputation of missing variance data using non-linear mixed effects modelling to enable an inverse variance weighted meta-analysis of summary-level longitudinal data: a case study

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Revealing causal heterogeneity using time series analysis of ambulatory assessments: application to the association between depression and physical activity after myocardial infarction

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Ascorbic acid, alpha-tocopherol, and beta-carotene reduce oxidative stress and proinflammatory cytokines in mononuclear cells of Alzheimer's disease patients.

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

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12 December 2020

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Statins reduce the expression of proinflammatory cytokines in influenza A virus infected CrFK cells

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Overview of Statistical Methods for Genome-Wide Association Studies (GWAS).

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Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults

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https://pubmed.ncbi.nlm.nih.gov/31024619

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Prevention of type 2 diabetes mellitus: is it feasible?

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Bioinformatics challenges in genome-wide association studies (GWAS).

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CLU rs2279590 polymorphism contributes to Alzheimer's disease susceptibility in Caucasian and Asian populations

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12 December 2020

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An overview of SNP interactions in genome-wide association studies

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Islet inflammation in human type 1 diabetes mellitus

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12 December 2020

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Genetic study of complex diseases in the post-GWAS era.

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Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

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12 December 2020

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Exploring linkage disequilibrium.

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based on heuristic

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Prediction of MicroRNA-Disease Associations Based on Social Network Analysis Methods

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Adipose tissue inflammation in the pathogenesis of type 2 diabetes.

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Interleukin 18 (IL-18) as a target for immune intervention

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet inflammation in type 2 diabetes

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrative microRNA-gene expression network analysis in genetic hypercalciuric stone-forming rat kidney

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Inferring microRNA-disease associations by random walk on a heterogeneous network with multiple data sources

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Mendelian Randomization as an Approach to Assess Causality Using Observational Data

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based on heuristic

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OAHG: an integrated resource for annotating human genes with multi-level ontologies.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

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Islet inflammation in type 2 diabetes and physiology

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

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Comparison of Two Meta-Analysis Methods: Inverse-Variance-Weighted Average and Weighted Sum of Z-Scores

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A novel hierarchical selective ensemble classifier with bioinformatics application

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based on heuristic

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Improved prediction of protein-protein interactions using novel negative samples, features, and an ensemble classifier.

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12 December 2020

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Residual Confounding or Lack of Effect?

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Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study

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12 December 2020

based on heuristic

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Spiking Neural P systems with Scheduled Synapses

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

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rSalvador: An R Package for the Fluctuation Experiment

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mendelian Randomization

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

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Proinflammatory cytokines correlate with early exercise attenuating anxiety-like behavior after cerebral ischemia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

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Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent Developments in Mendelian Randomization Studies

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probability-based collaborative filtering model for predicting gene-disease associations

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

InfAcrOnt: calculating cross-ontology term similarities using information flow by a random walk.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DincRNA: a comprehensive web-based bioinformatics toolkit for exploring disease associations and ncRNA function.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Novel Computational Method for Detecting DNA Methylation Sites with DNA Sequence Information and Physicochemical Properties

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive Approach for SNP Calling and Haplotype Assembly Using Single Molecular Sequencing Data.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of potential disease-associated microRNAs using structural perturbation method.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ACPred-FL: a sequence-based predictor using effective feature representation to improve the prediction of anti-cancer peptides

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HBPred: a tool to identify growth hormone-binding proteins.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-Path Methods for Prioritizing Candidate Disease miRNAs

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MOEA/HD: A Multiobjective Evolutionary Algorithm Based on Hierarchical Decomposition

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12 December 2020

based on heuristic

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An Evolutionary Algorithm Based on Minkowski Distance for Many-Objective Optimization

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12 December 2020

based on heuristic

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iRNA-2OM: A Sequence-Based Predictor for Identifying 2'-O-Methylation Sites in Homo sapiens

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

iTerm-PseKNC: a sequence-based tool for predicting bacterial transcriptional terminators

1 reference

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PubMed

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12 December 2020

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inferred from PubMed ID database lookup

A Parallel Workflow Pattern Modelling Using Spiking Neural P Systems with Colored Spikes

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12 December 2020

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inferred from PubMed ID database lookup

Human Disease System Biology

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse

1 reference

stated in

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identify origin of replication in Saccharomyces cerevisiae using two-step feature selection technique

1 reference

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12 December 2020

based on heuristic

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Predicting Diabetes Mellitus With Machine Learning Techniques

1 reference

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reference URL

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDA-SKF: Similarity Kernel Fusion for Accurately Discovering miRNA-Disease Association

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposing the Causal Effect of C-Reactive Protein on the Risk of Type 2 Diabetes Mellitus: A Mendelian Randomization Study

1 reference

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https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposing the Causal Effect of Body Mass Index on the Risk of Type 2 Diabetes Mellitus: A Mendelian Randomization Study

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/31024619

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

DOI

10.3389/FGENE.2019.00295

1 reference

stated in

Europe PubMed Central

PMC publication ID

6459887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31024619%20AND%20SRC:MED&resulttype=core&format=json

retrieved

23 April 2020

PMC publication ID

6459887

1 reference

stated in

Europe PubMed Central

PMC publication ID

6459887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31024619%20AND%20SRC:MED&resulttype=core&format=json

retrieved

23 April 2020

PubMed publication ID

31024619

1 reference

stated in

Europe PubMed Central

PMC publication ID

6459887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31024619%20AND%20SRC:MED&resulttype=core&format=json

retrieved

23 April 2020

 

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