The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis. (Q53922746)

22 May 2018

title

The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis. (English)

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22 May 2018

0 references

1 reference

Rob Pieters

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22 May 2018

Max M van Noesel

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22 May 2018

P A Voûte

series ordinal

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22 May 2018

Rogier Versteeg

series ordinal

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22 May 2018

language of work or name

English

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publication date

1 July 2003

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22 May 2018

published in

Cancer Letters

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22 May 2018

volume

197

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22 May 2018

issue

1-2

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22 May 2018

page(s)

165-172

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22 May 2018

Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death

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7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

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7 January 2021

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

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Proliferation, cell cycle and apoptosis in cancer

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7 January 2021

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

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7 January 2021

Apoptosis, cancer and cancer therapy.

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7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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7 January 2021

BID: a novel BH3 domain-only death agonist

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7 January 2021

Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

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7 January 2021

The survivin:Fas ratio is predictive of recurrent disease in neuroblastoma

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7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

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7 January 2021

MycN sensitizes neuroblastoma cells for drug-induced apoptosis

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis

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Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

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7 January 2021

Action of Myc in vivo - proliferation and apoptosis

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Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

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Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

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7 January 2021

10.1016/S0304-3835(03)00101-0

Identifiers

DOI

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22 May 2018

1 reference

22 May 2018