No endogenous A beta production in presenilin-deficient fibroblasts. (Q53921656)

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English	No endogenous A beta production in presenilin-deficient fibroblasts.	scientific article

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Europe PubMed Central

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12105423

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22 May 2018

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title

No endogenous A beta production in presenilin-deficient fibroblasts. (English)

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12105423

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22 May 2018

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Bart De Strooper

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9

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Bart De Strooper

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12105423

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22 May 2018

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Omar Nyabi

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1

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12105423

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22 May 2018

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Stefan Pype

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2

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12105423

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22 May 2018

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Marc Mercken

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An Herreman

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Paul Saftig

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Katleen Craessaerts

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12105423

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22 May 2018

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Lutgarde Serneels

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7

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12105423

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22 May 2018

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Wim Annaert

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8

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12105423

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publication date

1 July 2002

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published in

Nature Cell Biology

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volume

4

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22 May 2018

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issue

7

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22 May 2018

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http://europepmc.org/abstract/MED/12105423

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E164; author reply E165-6

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cites work

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

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Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay

1 reference

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Crossref

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https://api.crossref.org/works/10.1038%2FNCB0702-E164A

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7 January 2021

based on heuristic

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Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of presenilin-independent Notch signaling

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

stated in

Crossref

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https://api.crossref.org/works/10.1038%2FNCB0702-E164A

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiop

1 reference

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Crossref

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https://api.crossref.org/works/10.1038%2FNCB0702-E164A

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7 January 2021

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Identifiers

DOI

10.1038/NCB0702-E164A

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Europe PubMed Central

PubMed publication ID

12105423

retrieved

22 May 2018

reference URL

http://europepmc.org/abstract/MED/12105423

PubMed publication ID

12105423

1 reference

stated in

Europe PubMed Central

PubMed publication ID

12105423

retrieved

22 May 2018

reference URL

http://europepmc.org/abstract/MED/12105423

 

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