Stimulant and blocking effects of optical isomers of pindolol on the sinoatrial node and trachea of guinea pig. Role of ?-adrenoceptor subtypes in the dissociation between blockade and stimulation (Q53909390)

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scientific article published on September 1, 1984

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English	Stimulant and blocking effects of optical isomers of pindolol on the sinoatrial node and trachea of guinea pig. Role of ?-adrenoceptor subtypes in the dissociation between blockade and stimulation	scientific article published on September 1, 1984

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

Stimulant and blocking effects of optical isomers of pindolol on the sinoatrial node and trachea of guinea pig. Role of ?-adrenoceptor subtypes in the dissociation between blockade and stimulation (English)

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most precise value

1 reference

10.1007/BF00500912

https://api.crossref.org/works/10.1007/BF00500912

3 August 2023

Stimulant and blocking effects of optical isomers of pindolol on the sinoatrial node and trachea of guinea pig. Role of beta-adrenoceptor subtypes in the dissociation between blockade and stimulation (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6092972

3 August 2023

1 reference

10.1007/BF00500912

https://api.crossref.org/works/10.1007/BF00500912

3 August 2023

author name string

M. Walter

1

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6092972

3 August 2023

H. Lemoine

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6092972

3 August 2023

A. J. Kaumann

3

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3 August 2023

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National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6092972

3 August 2023

publication date

1 September 1984

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

full work available at URL

http://link.springer.com/content/pdf/10.1007/BF00500912.pdf

Portable Document Format

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10.1007/BF00500912

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3 August 2023

http://link.springer.com/article/10.1007/BF00500912/fulltext.html

1 reference

10.1007/BF00500912

https://api.crossref.org/works/10.1007/BF00500912

3 August 2023

http://link.springer.com/content/pdf/10.1007/BF00500912

1 reference

10.1007/BF00500912

https://api.crossref.org/works/10.1007/BF00500912

3 August 2023

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

327

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

2

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

159-175

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

Stimulant and depressant effects of beta-adrenoceptor blocking agents on isolated heart muscle. A positive inotropic effect not mediated through andrenoceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Differential distribution of beta-1 and beta-2 adrenergic receptors in cat and guinea-pig heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Cardiac beta receptors--experimental aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Direct labelling of myocardial beta 1-adrenoceptors. Comparison of binding affinity of 3H-(-)-bisoprolol with its blocking potency

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

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Beta-adrenoceptor antagonists in psychiatry and neurology

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

based on heuristic

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A model for the interaction of competitive antagonists with two receptor-subtypes characterized by a Schild-plot with apparent slope unity. Agonist-dependent enantiomeric affinity ratios for bupranolol in tracheae but not in right atria of guinea pi

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Receptors for 5-hydroxytryptamine on the sympathetic nerves of the rabbit heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

based on heuristic

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Different steric characteristics of ?1- and ?2-adrenoceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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3H-(?)-Bupranolol, a new ?-adrenoceptor radioligand: Characterization of its binding to kitten heart ?-adrenoceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

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Some quantitative uses of drug antagonists

1 reference

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The pharmacology of cimetidine, a new histamine H2-receptor antagonist

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Characterization of [3H](+/-)carazolol binding to beta-adrenergic receptors. Application to study of beta-adrenergic receptor subtypes in canine ventricular myocardium and lung

1 reference

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Evidence that ICI 118, 551 is a potent, highly Beta 2-selective adrenoceptor antagonist and can be used to characterize Beta-adrenoceptor populations in tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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beta-Adrenoceptor blocking agents as partial agonists in isolated heart muscle: dissociation of stimulation and blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

based on heuristic

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Evidence that (+)-bupranolol interacts directly with myocardial beta-adrenoceptors. Control of optical purity with differential thermal analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

based on heuristic

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The importance of choice of agonist in studies designed to predict ? 2:? 1 adrenoceptor selectivity of antagonists from pA2 values on guinea-pig trachea and atria

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Convenient apparatus for recording contractions of isolated heart muscle

1 reference

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The Uptake of Atropine and Related Drugs by Intestinal Smooth Muscle of the Guinea-Pig in Relation to Acetylcholine Receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

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A study of beta-adrenoceptors in the guinea pig

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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On spare ?-adrenoceptors for inotropic effects of catecholamines in kitten ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Intrinsic sympathomimetic activity of beta-blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Effects of pindolol on vascular smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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Comparative assessment of?-adrenoceptor blocking agents as simple competitive antagonists in isolated heart muscle: Similarity of inotropic and chronotropic blocking potencies against isoproterenol

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

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A comparison of the influence of N-isopropyl and N-tert butyl substituents on the affinity of ligands for sinoatrial ?-adrenoceptors in rat atria and ?-adrenoceptors coupled to the adenylyl cyclase in kitten ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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The Pharmacology of a β2-Selective Adrenoceptor Antagonist (ICI 118,551)

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

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The action of histamine and 5-hydroxytryptamine on isolated mammalian atria

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Yohimbine and rauwolscine inhibit 5-hydroxytryptamine-induced contraction of large coronary arteries of calf through blockade of 5 HT2 receptors

1 reference

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12 December 2020

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Are the pA2 values of selective beta-adrenoceptor antagonists valid when obtained on guinea-pig tracheal preparations contracted with carbachol?

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

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A study of the relationship between cardiac ?-adrenoceptor blockade and intrinsic sympathomimetic activity in rats depleted of catecholamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

12 December 2020

based on heuristic

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A novel analysis of concentration-dependence of partial agonism Ring-demethylation of bupranolol results in a high affinity partial agonist (K 105) for myocardial and tracheal beta-adrenoceptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6092972

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Proceedings: Two types of intrinsic sympathomimetic activity with beta-adrenoceptor blocking drugs

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Studies on receptor-mediated activation of adenylyl cyclases. IV. Characteristics of the adrenergic receptor coupled to myocardial adenylyl cyclase: stereospecificity for ligands and determination of apparent affinity constants for beta-blockers

1 reference

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On the statistics of drug-receptor constants for partial agonists

1 reference

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based on heuristic

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Iodohydroxybenzylpindolol: preparation, purification, localization of its iodine to the indole ring, and characterization as a partial agonist

1 reference

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Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones

1 reference

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British Journal of Pharmacology

1

14

48

author name string

O Arunlakshana

publication date

1959

1 reference

10.1007/BF00500912

https://api.crossref.org/works/10.1007/BF00500912

3 August 2023

Molecular Pharmacology

3

17

328

author name string

CF Bearer

publication date

1980

1 reference

10.1007/BF00500912

https://api.crossref.org/works/10.1007/BF00500912

3 August 2023

British Journal of Pharmacology

9

53

435

author name string

RW Brimblecombe

publication date

1975

1 reference

10.1007/BF00500912

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3 August 2023

Mode of action of gamma-butyrolactone on the central cholinergic system.

21

1 reference

10.1007/BF00500912

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3 August 2023

Direct labelling of myocardial ? 1-adrenoceptors

29

1 reference

10.1007/BF00500912

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3 August 2023

Direct labelling of beta 2-adrenoceptors. Comparison of binding potency of 3H-ICI 118,551 and blocking potency of ICI 118,551

35

1 reference

10.1007/BF00500912

https://api.crossref.org/works/10.1007/BF00500912

3 August 2023

Identifiers

10.1007/BF00500912

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 May 2018

http://europepmc.org/abstract/MED/6092972

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