Distinguishing between resistance, tolerance and persistence to antibiotic treatment. (Q53789924)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Distinguishing between resistance, tolerance and persistence to antibiotic treatment (English)

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1 April 2020

main subject

antibiotic resistance

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Asher Brauner

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Ofer Fridman

series ordinal

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1 April 2020

language of work or name

English

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publication date

1 April 2016

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Microbiology

1 April 2020

published in

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volume

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issue

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1 April 2020

page(s)

320-330

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json

Microbial and viral drug resistance mechanisms

1 April 2020

cites work

1 reference

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Sampling the antibiotic resistome

31 March 2020

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TREATMENT OF STAPHYLOCOCCAL INFECTIONS WITH PENICILLIN BY INTERMITTENT STERILISATION

31 March 2020

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Tolerant response of Streptococcus sanguis to beta-lactams and other cell wall inhibitors

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A problem of persistence: still more questions than answers?

31 March 2020

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Persisters and beyond: mechanisms of phenotypic drug resistance and drug tolerance in bacteria

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Antibiotic tolerance among clinical isolates of bacteria

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Concentration of biochemical mutants of bacteria with penicillin

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The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress.

31 March 2020

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Bacterial persistence as a phenotypic switch

31 March 2020

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Dynamic persistence of antibiotic-stressed mycobacteria

31 March 2020

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Modes and modulations of antibiotic resistance gene expression

31 March 2020

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Molecular mechanisms of antibiotic resistance.

31 March 2020

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Antibiotic interactions that select against resistance

31 March 2020

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Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

31 March 2020

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Antibiotic efficacy in vivo predicted by in vitro activity

31 March 2020

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Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory.

31 March 2020

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Variables in demonstrating methicillin tolerance in Staphylococcus aureus strains

31 March 2020

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Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and beta-lactam antimicrobial agents

31 March 2020

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Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC

31 March 2020

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Persister cells and tolerance to antimicrobials

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Bactericidal activity of oxacillin and glycopeptides against Staphylococcus aureus in patients with endocarditis: looking for a relationship between tolerance and outcome

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations.

31 March 2020

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Pharmacodynamic functions: a multiparameter approach to the design of antibiotic treatment regimens

31 March 2020

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Single-cell protein induction dynamics reveals a period of vulnerability to antibiotics in persister bacteria.

31 March 2020

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Dynamics of intracellular bacterial replication at the single cell level.

31 March 2020

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Metabolic control of persister formation in Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Structured habitats and the evolution of anticompetitor toxins in bacteria

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Effects of inhibitors of protein synthesis on lysis of Escherichia coli induced by beta-lactam antibiotics.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Dormancy is not necessary or sufficient for bacterial persistence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Antagonism between penicillin and erythromycin against Streptococcus pneumoniae in vitro and in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Ampicillin susceptibility and ampicillin-induced killing rate of Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Bactericidal action of daptomycin against stationary-phase and nondividing Staphylococcus aureus cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Time-kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Susceptibility of Pseudomonas aeruginosa and Escherichia coli biofilms towards ciprofloxacin: effect of specific growth rate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Intra- and extracellular activities of dicloxacillin against Staphylococcus aureus in vivo and in vitro.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Endopeptidase-mediated beta lactam tolerance

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Antibiotic treatment in vitro of phenotypically tolerant bacterial populations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Direct observation of single stationary-phase bacteria reveals a surprisingly long period of constant protein production activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Persister cells, dormancy and infectious disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Automated imaging with ScanLag reveals previously undetectable bacterial growth phenotypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Age of inoculum strongly influences persister frequency and can mask effects of mutations implicated in altered persistence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Promoter activity dynamics in the lag phase of Escherichia coli.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

The frequency of persisters in Escherichia coli reflects the kinetics of awakening from dormancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Phenotypic heterogeneity enables uropathogenic Escherichia coli to evade killing by antibiotics and serum complement

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Nongenetic individuality in the host-phage interaction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Stochastic modelling of bacterial lag phase.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Analysis of cell size and DNA content in exponentially growing and stationary-phase batch cultures of Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Non-inherited antibiotic resistance.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: effects on macromolecular synthesis and persister formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Stochastic expression of a multiple antibiotic resistance activator confers transient resistance in single cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Antimicrobial heteroresistance: an emerging field in need of clarity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Comparison of the antibacterial effects of cefepime and ceftazidime against Escherichia coli in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Targeting non-multiplying organisms as a way to develop novel antimicrobials

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Identification of novel activity against Borrelia burgdorferi persisters using an FDA approved drug library

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Selective killing of bacterial persisters by a single chemical compound without affecting normal antibiotic-sensitive cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

A screen for and validation of prodrug antimicrobials

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Activated ClpP kills persisters and eradicates a chronic biofilm infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Cell division in Escherichia coli cultures monitored at single cell resolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Phenotypic variation of Salmonella in host tissues delays eradication by antimicrobial chemotherapy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Tobramycin resistance of Pseudomonas aeruginosa cells growing as a biofilm on urinary catheter material

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Signals of growth regulation in bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Bacterial persistence: some new insights into an old phenomenon

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Microbial persistence and the road to drug resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

31 March 2020

(p)ppGpp: still magical?

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Molecular mechanism of bacterial persistence by HipA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

ComGA-RelA interaction and persistence in the Bacillus subtilis K-state.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Bacterial persistence and toxin-antitoxin loci

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Large mutational target size for rapid emergence of bacterial persistence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

GlpD and PlsB participate in persister cell formation in Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Increased persistence in Escherichia coli caused by controlled expression of toxins or other unrelated proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Genetic basis of persister tolerance to aminoglycosides in Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Persistence: mechanisms for triggering and enhancing phenotypic variability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Programmed heterogeneity: epigenetic mechanisms in bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Non-genetic heterogeneity from stochastic partitioning at cell division

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

A general model for toxin-antitoxin module dynamics can explain persister cell formation in E. coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Bacterial persistence by RNA endonucleases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Internalization of Salmonella by macrophages induces formation of nonreplicating persisters.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

How sisters grow apart: mycobacterial growth and division

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Role of oxidative stress in persister tolerance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Additional routes to Staphylococcus aureus daptomycin resistance as revealed by comparative genome sequencing, transcriptional profiling, and phenotypic studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Single-cell microbiology: tools, technologies, and applications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Robust growth of Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Design of a large-scale femtoliter droplet array for single-cell analysis of drug-tolerant and drug-resistant bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Persisters: a distinct physiological state of E. coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Establishment of a method to rapidly assay bacterial persister metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Heterogeneity of methicillin-resistant Staphylococcus aureus strains (MRSA) characterized by flow cytometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2016.34

Pharmacokinetic and pharmacodynamic models of the antistaphylococcal effects of meropenem and cloxacillin in vitro and in experimental infection

31 March 2020

1 reference

12 December 2020

The rate of killing of Escherichia coli by beta-lactam antibiotics is strictly proportional to the rate of bacterial growth.

1 reference

12 December 2020

Microbial persistence.

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12 December 2020

Escherichia coli Mutants Tolerant to Beta-Lactam Antibiotics

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12 December 2020

hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis

1 reference

12 December 2020

Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells

1 reference

12 December 2020

Acquired and Native Resistance of Staphylococcus aureus to Cephalexin and Other β-Lactam Antibiotics

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRMICRO.2016.34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27080241%20AND%20SRC:MED&resulttype=core&format=json