Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations. (Q53556700)

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English	Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations.	scientific article

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6318112

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15 May 2018

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Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations. (English)

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6318112

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Sukumar S

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6318112

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Notario V

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6318112

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Martin-Zanca D

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6318112

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Barbacid M

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1 December 1983

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6318112

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Nature

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6318112

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volume

306

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6318112

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5944

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6318112

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658-661

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Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

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T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

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Three human transforming genes are related to the viral ras oncogenes

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Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype

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Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

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Generation of BALB-MuSV and Ha-MuSV by type C virus transduction of homologous transforming genes from different species

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The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

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Structure and functions of the Kirsten murine sarcoma virus genome: molecular cloning of biologically active Kirsten murine sarcoma virus DNA.

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Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus

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Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

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Mechanism of activation of a human oncogene

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A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

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Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change.

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Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

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Nucleotide sequence analysis of the T24 human bladder carcinoma oncogene

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Spontaneous activation of a human proto-oncogene

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Prediction of the three-dimensional structure of the transforming region of the EJ/T24 human bladder oncogene product and its normal cellular homologue

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Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene

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Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1.

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Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene

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Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

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Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene

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Detection of specific sequences among DNA fragments separated by gel electrophoresis

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Identifiers

DOI

10.1038/306658A0

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stated in

Europe PubMed Central

PubMed publication ID

6318112

retrieved

15 May 2018

reference URL

http://europepmc.org/abstract/MED/6318112

Dimensions Publication ID

1011532894

0 references

PubMed publication ID

6318112

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6318112

retrieved

15 May 2018

reference URL

http://europepmc.org/abstract/MED/6318112

 

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