Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion. (Q53499112)

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scientific article published on 9 February 2008

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English	Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.	scientific article published on 9 February 2008

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

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http://europepmc.org/abstract/MED/18264689

title

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion. (English)

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Europe PubMed Central

PubMed publication ID

18264689

retrieved

14 May 2018

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http://europepmc.org/abstract/MED/18264689

author

Harald Staiger

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6

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Europe PubMed Central

PubMed publication ID

18264689

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Norbert Stefan

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7

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PubMed publication ID

18264689

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14 May 2018

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http://europepmc.org/abstract/MED/18264689

Andreas Fritsche

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9

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A Fritsche

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

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Fausto Machicao

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2

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F Machicao

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

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http://europepmc.org/abstract/MED/18264689

Hans-Ulrich Häring

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H-U Häring

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Europe PubMed Central

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18264689

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14 May 2018

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K Kirchhoff

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1

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

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http://europepmc.org/abstract/MED/18264689

A Haupt

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3

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

S A Schäfer

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4

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

O Tschritter

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5

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

publication date

9 February 2008

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

published in

Diabetologia

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

volume

51

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

issue

4

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Europe PubMed Central

PubMed publication ID

18264689

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14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

page(s)

597-601

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18264689

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14 May 2018

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http://europepmc.org/abstract/MED/18264689

cites work

Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative hyperproinsulinemia as a sign of islet dysfunction in women with impaired glucose tolerance.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence against a rate-limiting role of proinsulin processing for maximal insulin secretion in subjects with impaired glucose tolerance and beta-cell dysfunction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18264689

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00125-008-0926-Y

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18264689

retrieved

14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

PubMed publication ID

18264689

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18264689

retrieved

14 May 2018

reference URL

http://europepmc.org/abstract/MED/18264689

ResearchGate publication ID

5586802

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