2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses apoptosis and leads to hyperphosphorylation of p53 in rat hepatocytes (Q53428667)

14 May 2018

title

2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses apoptosis and leads to hyperphosphorylation of p53 in rat hepatocytes (English)

1 reference

https://api.crossref.org/works/10.1016/S1382-6689(98)00040-4

7 December 2024

W. Wörner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21781900

7 December 2024

D. Schrenk

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21781900

7 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21781900

7 December 2024

publication date

1 December 1998

1 reference

14 May 2018

full work available at URL

https://api.elsevier.com/content/article/PII:S1382668998000404?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1382-6689(98)00040-4

https://api.elsevier.com/content/article/PII:S1382668998000404?httpAccept=text/plain

7 December 2024

1 reference

https://api.crossref.org/works/10.1016/S1382-6689(98)00040-4

Environmental Toxicology and Pharmacology

7 December 2024

published in

1 reference

14 May 2018

volume

1 reference

14 May 2018

issue

1 reference

14 May 2018

page(s)

239-247

1 reference

14 May 2018

The liver-specific response to phenobarbital involves a transient increase in phosphorylation of a 34-kda nuclear protein in rat liver and in hepatocytes in culture

cites work

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7 January 2021

The ability to alter the gap junction protein expression outside GST-P positive foci in liver of rats was associated to the tumour promotion potency of different polychlorinated biphenyls

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7 January 2021

Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin

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7 January 2021

Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters

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7 January 2021

Evidence for a second pathway in the action mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Significance of Ah-receptor mediated activation of protein kinase under cell-free conditions

1 reference

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7 January 2021

Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway

1 reference

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7 January 2021

Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation

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7 January 2021

p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

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7 January 2021

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

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7 January 2021

Constitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogene

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7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

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7 January 2021

Nuclear protein phosphorylation and growth control

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7 January 2021

Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction.

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7 January 2021

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1

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7 January 2021

2,3,7,8-Tetrachlorodibenzo-p-dioxin and ethinylestradiol as co-mitogens in cultured rat hepatocytes

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7 January 2021

Promotion of preneoplastic foci in rat liver with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 1,2,3,4,6,7,8-heptachloro-dibenzo-p-dioxin and a defined mixture of 49 polychlorinated dibenzo-p-dioxins

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7 January 2021

Tumor promotion in the liver

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7 January 2021

GST-P-positive hepatocytes isolated from rats bearing enzyme-altered foci show no signs of p53 protein induction and replicate even when their DNA contains strand breaks

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7 January 2021

Inhibition of apoptosis during 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated tumour promotion in rat liver

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7 January 2021

Association of insulin-like growth-factor-I-induced DNA synthesis with phosphorylation and nuclear exclusion of p53 in human breast cancer MCF-7 cells

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7 January 2021

Inhibition of radiation-induced apoptosis in vitro by tumor promoters

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7 January 2021

Recovery from ultraviolet-induced growth arrest of primary rat hepatocytes by p53 antisense oligonucleotide treatment

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7 January 2021

Inhibition of epidermal growth factor receptor biosynthesis caused by the src oncogene product, pp60v-src

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7 January 2021

Accumulation of p53 protein in chemically induced oval cells during early stages of rodent hepatocarcinogenesis

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7 January 2021

Nicotine inhibition of apoptosis suggests a role in tumor promotion.

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7 January 2021

Inhibition of apoptosis as a mechanism of tumor promotion

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7 January 2021

Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents

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p53 phosphorylation mutants retain transcription activity

7 December 2024

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Participation of p53 protein in the cellular response to DNA damage

7 December 2024

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Protein measurement with the Folin phenol reagent

7 December 2024

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Ovarian hormones enhance 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated increases in cell proliferation and preneoplastic foci in a two-stage model for rat hepatocarcinogenesis

7 December 2024

1 reference

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DNA-damaging agents induce both p53-dependent and p53-independent apoptosis in immature thymocytes

7 December 2024

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Murine p53 is phosphorylated within the PAb421 epitope by protein kinase C in vitro, but not in vivo, even after stimulation with the phorbol ester o-tetradecanoylphorbol 13-acetate

7 December 2024

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The stages of initiation and promotion in hepatocarcinogenesis

7 December 2024

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Polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin induce intrachromosomal recombination in vitro and in vivo

7 December 2024

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Enhanced proliferation of putative preneoplastic cells in rat liver following treatment with the tumor promoters phenobarbital, hexachlorocyclohexane, steroid compounds, and nafenopin

7 December 2024

1 reference

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Tumor-promoting phorbol ester transiently down-modulates the p53 level and blocks the cell cycle

7 December 2024

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Hyperphosphorylation of retinoblastoma protein and p53 by okadaic acid, a tumor promoter

7 December 2024

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Hyperphosphorylation of p53 induced by okadaic acid attenuates its transcriptional activation function

7 December 2024

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7 December 2024

Identifiers

1 reference

14 May 2018

1 reference

14 May 2018