Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes. (Q53364131)

13 May 2018

title

Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes. (English)

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13 May 2018

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13 May 2018

author name string

Joo-Won Park

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13 May 2018

Woo-Jae Park

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13 May 2018

Yael Kuperman

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13 May 2018

Sigalit Boura-Halfon

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13 May 2018

Yael Pewzner-Jung

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13 May 2018

language of work or name

English

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publication date

6 December 2012

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13 May 2018

published in

Hepatology

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13 May 2018

volume

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issue

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13 May 2018

page(s)

525-532

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13 May 2018

A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing's syndrome

cites work

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Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

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Sphingomyelinase and ceramide suppress insulin-induced tyrosine phosphorylation of the insulin receptor substrate-1

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7 January 2021

Ceramide synthase inhibition by fumonisin B1 treatment activates sphingolipid-metabolizing systems in mouse liver

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Lipid rafts and insulin signaling

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Involvement of very long fatty acid-containing lactosylceramide in lactosylceramide-mediated superoxide generation and migration in neutrophils

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Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

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Sirtuins as regulators of metabolism and healthspan

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Identifiers

DOI

10.1002/HEP.26015

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13 May 2018

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13 May 2018