Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression. (Q53296362)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935679%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression (English)

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15 February 2020

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15 February 2020

J Ahn

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15 February 2020

M Ko

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15 February 2020

C Lee

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15 February 2020

J Kim

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15 February 2020

H Yoon

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15 February 2020

language of work or name

English

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publication date

11 October 2010

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15 February 2020

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15 February 2020

volume

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15 February 2020

issue

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15 February 2020

page(s)

445-456

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Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

15 February 2020

cites work

1 reference

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A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

21 January 2018

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Characterization of mammary tumors from Brg1 heterozygous mice.

21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

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Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair

21 January 2018

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Regulating SWI/SNF subunit levels via protein-protein interactions and proteasomal degradation: BAF155 and BAF170 limit expression of BAF57

21 January 2018

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Tumorigenic activity of p21Waf1/Cip1 in thymic lymphoma.

21 January 2018

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Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers

21 January 2018

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Loss of the INI1 tumor suppressor does not impair the expression of multiple BRG1-dependent genes or the assembly of SWI/SNF enzymes

21 January 2018

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

21 January 2018

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Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter

21 January 2018

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Targeted knockout of BRG1 potentiates lung cancer development

21 January 2018

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Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

21 January 2018

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SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development.

21 January 2018

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Peripheral T cells become sensitive to glucocorticoid- and stress-induced apoptosis in transgenic mice overexpressing SRG3.

21 January 2018

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Role for BRG1 in cell cycle control and tumor suppression

21 January 2018

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Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins

21 January 2018

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Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

21 January 2018

1 reference

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Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development

21 January 2018

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The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

21 January 2018

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Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex

21 January 2018

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Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

21 January 2018

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Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability.

21 January 2018

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Functional differentiation of SWI/SNF remodelers in transcription and cell cycle control

21 January 2018

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BAF60a interacts with p53 to recruit the SWI/SNF complex

21 January 2018

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Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction

21 January 2018

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Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

21 January 2018

1 reference

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Genetic determinants of p53-induced apoptosis and growth arrest

21 January 2018

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21 January 2018

1 reference

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Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

21 January 2018

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The SWI/SNF complex--chromatin and cancer.

21 January 2018

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DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

21 January 2018

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Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

21 January 2018

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Dissecting p53 tumor suppressor functions in vivo

21 January 2018

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Integral role of Noxa in p53-mediated apoptotic response

21 January 2018

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SRG3 interacts directly with the major components of the SWI/SNF chromatin remodeling complex and protects them from proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.424

BRG-1 is required for RB-mediated cell cycle arrest

21 January 2018

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RB and hbrm cooperate to repress the activation functions of E2F1

21 January 2018

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Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

21 January 2018

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Outcomes of p53 activation--spoilt for choice

21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

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Cancer-associated mutations in chromatin remodeler hSNF5 promote chromosomal instability by compromising the mitotic checkpoint.

21 January 2018

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Loss of p 21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm -deficient mice

21 January 2018

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Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement

21 January 2018

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Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.

21 January 2018

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

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Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies

21 January 2018

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Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5

31 March 2020

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p53-dependent apoptosis suppresses tumor growth and progression in vivo

31 March 2020

1 reference

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935679%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20935679%20AND%20SRC:MED&resulttype=core&format=json