Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies. (Q52887959)

9 May 2018

title

Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies. (English)

1 reference

9 May 2018

1 reference

1 reference

Katrin Zeilinger

1 reference

9 May 2018

author name string

Stefan A Hoffmann

1 reference

9 May 2018

Ursula Müller-Vieira

1 reference

9 May 2018

Klaus Biemel

1 reference

9 May 2018

Daniel Knobeloch

1 reference

9 May 2018

Sandra Heydel

1 reference

9 May 2018

Marc Lübberstedt

1 reference

9 May 2018

Andreas K Nüssler

1 reference

9 May 2018

Tommy B Andersson

1 reference

9 May 2018

Jörg C Gerlach

1 reference

9 May 2018

publication date

27 June 2012

1 reference

9 May 2018

Biotechnology and Bioengineering

published in

1 reference

9 May 2018

volume

109

1 reference

9 May 2018

issue

1 reference

9 May 2018

page(s)

3172-3181

1 reference

9 May 2018

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

cites work

1 reference

Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways

21 January 2018

1 reference

Dynamic seeding and perfusion culture of hepatocytes with galactosylated vegetable sponge in packed-bed bioreactor

21 January 2018

1 reference

Human hepatocyte functions in a crossed hollow fiber membrane bioreactor

21 January 2018

1 reference

The involvement of Kupffer cells in carbon tetrachloride toxicity

21 January 2018

1 reference

Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study

21 January 2018

1 reference

Cellular interactions promote tissue-specific function, biomatrix deposition and junctional communication of primary cultured hepatocytes

21 January 2018

1 reference

Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions

21 January 2018

1 reference

3D hepatic cultures simultaneously maintain primary hepatocyte and liver sinusoidal endothelial cell phenotypes

21 January 2018

1 reference

Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac

21 January 2018

1 reference

Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide

21 January 2018

1 reference

Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benzbromarone

21 January 2018

1 reference

Extending hepatocyte functionality for drug-testing applications using high-viscosity alginate-encapsulated three-dimensional cultures in bioreactors

21 January 2018

1 reference

Hepatocyte dynamics in a three-dimensional rotating bioreactor

21 January 2018

1 reference

The effectiveness of a novel cartridge-based bioreactor design in supporting liver cells

21 January 2018

1 reference

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

21 January 2018

1 reference

Primary human hepatocytes on biodegradable poly(l-lactic acid) matrices: A promising model for improving transplantation efficiency with tissue engineering

21 January 2018

1 reference

Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes.

21 January 2018

1 reference

Hepatotoxicity assay using human hepatocytes trapped in microholes of a microfluidic device

21 January 2018

1 reference

Time course of primary liver cell reorganization in three-dimensional high-density bioreactors for extracorporeal liver support: an immunohistochemical and ultrastructural study

21 January 2018

1 reference

Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies.

21 January 2018

1 reference

Human Hepatocytes: Isolation, Culture, and Quality Procedures

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BIT.24573

1 reference

9 May 2018

1 reference

9 May 2018