Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens. (Q52842432)

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scientific article published on 5 March 2003

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English	Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens.	scientific article published on 5 March 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens. (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

6

object named as

Paul E Bock

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

author name string

John J Flanagan

1

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

Jui-Chang Chen

2

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

Yiwei Miao

3

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

Yuanlong Shao

4

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

Jialing Lin

5

1 reference

Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

Arthur E Johnson

7

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

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publication date

5 March 2003

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

number of pages

10

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

278

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

20

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

18628-18637

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Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

The signal recognition particle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Towards the structure of the mammalian signal recognition particle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

The translocon: a dynamic gateway at the ER membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Signal sequences. The limits of variation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Discrete nascent chain lengths are required for the insertion of presecretory proteins into microsomal membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Both the 5' untranslated region and the sequences surrounding the start site contribute to efficient initiation of translation in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Protein translocation across the endoplasmic reticulum membrane: identification by photocross-linking of a 39-kD integral membrane glycoprotein as part of a putative translocation tunnel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Preparation of microsomal membranes for cotranslational protein translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Effects of nucleotide- and aurodox-induced changes in elongation factor Tu conformation upon its interactions with aminoacyl transfer RNA. A fluorescence study.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Reversible dissociation of wheat germ ribosomal subunits: cation-dependent equilibria and thermodynamic parameters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Direct determination of the association constant between elongation factor Tu X GTP and aminoacyl-tRNA using fluorescence.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Fluorescence characterization of the interaction of various transfer RNA species with elongation factor Tu.GTP: evidence for a new functional role for elongation factor Tu in protein biosynthesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Nepsilon-acetyllysine transfer ribonucleic acid: a biologically active analogue of aminoacyl transfer ribonucleic acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Intracellular signaling from the endoplasmic reticulum to the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

SRP samples nascent chains for the presenceof signal sequences by interacting with ribosomes at a discrete step during translation elongation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Fluorescence-detected assembly of the signal recognition particle: binding of the two SRP protein heterodimers to SRP RNA is noncooperative

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Distance moved by transfer RNA during translocation from the A site to the P site on the ribosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Both Lumenal and Cytosolic Gating of the Aqueous ER Translocon Pore Are Regulated from Inside the Ribosome during Membrane Protein Integration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300173200

21 January 2018

Inactivation of Thrombin by Antithrombin Is Accompanied by Inactivation of Regulatory Exosite I

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M300173200

1 reference

Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 May 2018

http://europepmc.org/abstract/MED/12621052

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