A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase. (Q52668830)

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scientific article published on 7 March 2018

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English	A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase.	scientific article published on 7 March 2018

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase. (English)

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

author name string

Jianbiao Zhou

1

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Sabrina Hui-Min Toh

2

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Zit-Liang Chan

3

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Jessie Yiying Quah

4

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Jing-Yuan Chooi

5

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Tuan Zea Tan

6

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Phyllis S Y Chong

7

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Qi Zeng

8

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Wee-Joo Chng

9

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Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

publication date

7 March 2018

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Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

Journal of Hematology & Oncology

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Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

11

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Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

1

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

36

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

PRL-3 promotes telomere deprotection and chromosomal instability

1 reference

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Emerging therapies for acute myeloid leukemia

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Molecular and genetic alterations associated with therapy resistance and relapse of acute myeloid leukemia

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Deletion of Ptp4a3 reduces clonogenicity and tumor-initiation ability of colitis-associated cancer cells in mice

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Picking the point of inhibition: a comparative review of PI3K/AKT/mTOR pathway inhibitors

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Independent oncogenic and therapeutic significance of phosphatase PRL-3 in FLT3-ITD-negative acute myeloid leukemia

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Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

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The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia

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10.1186/S13045-018-0581-9

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Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13045-018-0581-9

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 May 2018

http://europepmc.org/abstract/PMC/5842526

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