Presenilin mutations line up along transmembrane alpha-helices. (Q52543234)

3 May 2018

title

Presenilin mutations line up along transmembrane alpha-helices. (English)

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3 May 2018

main subject

transmembrane protein

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author name string

Hardy J

series ordinal

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3 May 2018

Crook R

series ordinal

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3 May 2018

language of work or name

English

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publication date

1 June 2001

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3 May 2018

published in

Neuroscience Letters

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3 May 2018

volume

306

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3 May 2018

issue

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3 May 2018

page(s)

203-205

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3 May 2018

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Early-onset Alzheimer's disease with a presenilin-1 mutation at the site corresponding to the Volga German presenilin-2 mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Molecular genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Amyloid, the presenilins and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

The presenilin 1 C92S mutation increases abeta 42 production.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases abeta 42 generation in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

A further presenilin 1 mutation in the exon 8 cluster in familial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3940%2801%2901910-3

7 January 2021

10.1016/S0304-3940(01)01910-3

Identifiers

DOI

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3 May 2018

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3 May 2018