Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio. (Q52546877)

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scientific article published on 31 July 2002

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English	Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.	scientific article published on 31 July 2002

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12151395%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12151395%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

apoptotic process

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inferred from title

Delphine Javelaud

1

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Europe PubMed Central

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11 November 2019

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Francoise Besancon

2

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11 November 2019

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31 July 2002

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11 November 2019

Journal of Biological Chemistry

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11 November 2019

277

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11 November 2019

40

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11 November 2019

37949-37954

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11 November 2019

Regulation of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Regulation of p53 function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

The cellular response to p53: the decision between life and death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

IkappaB kinase-dependent chronic activation of NF-kappaB is necessary for p21(WAF1/Cip1) inhibition of differentiation-induced apoptosis of monocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

A non-enzymatic p21 protein inhibitor of stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Mitochondria as targets for established and novel anti-cancer agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Life-or-death decisions by the Bcl-2 protein family.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

JNK targets p53 ubiquitination and degradation in nonstressed cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Apoptosis-based therapies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Regulation of cell proliferation by the E2F transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Human ARF binds E2F1 and inhibits its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

The INK4a/ARF network in tumour suppression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Rescuing the function of mutant p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204497200

21 January 2018

Identifiers

10.1074/JBC.M204497200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12151395%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12151395%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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