The dual mechanism of separase regulation by securin (Q52161908)

25 April 2018

title

The dual mechanism of separase regulation by securin (English)

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25 April 2018

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25 April 2018

author name string

Nadine C D Hornig

series ordinal

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25 April 2018

Philip P Knowles

series ordinal

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25 April 2018

Neil Q McDonald

series ordinal

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25 April 2018

language of work or name

English

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publication date

1 June 2002

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25 April 2018

published in

Current Biology

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25 April 2018

volume

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25 April 2018

issue

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25 April 2018

page(s)

973-982

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25 April 2018

Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis

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Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

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Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

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Requirement for ESP1 in the nuclear division of Saccharomyces cerevisiae

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The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene

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Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis.

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Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes.

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An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast

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A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1

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Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae

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Cell cycle mechanisms of sister chromatid separation; roles of Cut1/separin and Cut2/securin

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Secured cutting: controlling separase at the metaphase to anaphase transition

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Cut2 proteolysis required for sister-chromatid seperation in fission yeast

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Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p

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Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

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Dual inhibition of sister chromatid separation at metaphase

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Securin is required for chromosomal stability in human cells

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Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition

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Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast

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Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast

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Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs

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Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae

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Exportin 1 (Crm1p) is an essential nuclear export factor

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Drosophila separase is required for sister chromatid separation and binds to PIM and THR

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Dimer formation drives the activation of the cell death protease caspase 9

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Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast

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Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19

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7 January 2021

Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase

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New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

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Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

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Cohesion between sister chromatids must be established during DNA replication

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New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

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Cohesins: chromosomal proteins that prevent premature separation of sister chromatids

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7 January 2021

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Identifiers

DOI

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25 April 2018

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25 April 2018