pRB and p107 have distinct effects when expressed in pRB-deficient tumor cells at physiologically relevant levels. (Q52165868)

26 April 2018

title

pRB and p107 have distinct effects when expressed in pRB-deficient tumor cells at physiologically relevant levels. (English)

1 reference

26 April 2018

author name string

Jiang H

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26 April 2018

Karnezis AN

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26 April 2018

Tao M

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26 April 2018

Guida PM

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26 April 2018

Zhu L

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26 April 2018

language of work or name

English

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publication date

1 August 2000

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26 April 2018

published in

Oncogene

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26 April 2018

volume

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26 April 2018

issue

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26 April 2018

page(s)

3878-3887

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26 April 2018

Genomic structure of the human retinoblastoma-related Rb2/p130 gene

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1 reference

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E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

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Proteasome-dependent regulation of p21WAF1/CIP1 expression

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Regulation of cellular genes in a chromosomal context by the retinoblastoma tumor suppressor protein

21 January 2018

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Requirement for a functional Rb-1 gene in murine development

21 January 2018

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Shared role of the pRB-related p130 and p107 proteins in limb development

21 January 2018

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Cell cycle-specific association of E2F with the p130 E1A-binding protein

21 January 2018

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Association of p107 with Sp1: genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcription

21 January 2018

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Specific regulation of E2F family members by cyclin-dependent kinases

21 January 2018

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Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins

21 January 2018

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Interaction between human cyclin A and adenovirus E1A-associated p107 protein

21 January 2018

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Quantitation of RNA using the polymerase chain reaction

21 January 2018

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Differential regulation of the retinoblastoma family of proteins during cell proliferation and differentiation

21 January 2018

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E2F-4, a new member of the E2F transcription factor family, interacts with p107

21 January 2018

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The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

21 January 2018

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

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Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation

21 January 2018

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Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

21 January 2018

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E2F-5, a new E2F family member that interacts with p130 in vivo

21 January 2018

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Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

21 January 2018

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Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

21 January 2018

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pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

21 January 2018

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E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest

21 January 2018

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Effects of an Rb mutation in the mouse

21 January 2018

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Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

21 January 2018

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Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

21 January 2018

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Identification of a p130 domain mediating interactions with cyclin A/cdk 2 and cyclin E/cdk 2 complexes

21 January 2018

1 reference

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Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene.

21 January 2018

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 January 2018

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The retinoblastoma protein binds to a family of E2F transcription factors

21 January 2018

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Growth suppression by p16ink4 requires functional retinoblastoma protein

21 January 2018

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The retinoblastoma gene family: cousins with overlapping interests

21 January 2018

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Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle

21 January 2018

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

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Identification of a growth suppression domain within the retinoblastoma gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

Induction of DNA synthesis and apoptosis by regulated inactivation of a temperature-sensitive retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

pRB, p107 and the regulation of the E2F transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

inferred from DOI database lookup

7 January 2021

based on heuristic

Targeted disruption of p107: functional overlap between p107 and Rb

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203722

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1203722

1 reference

26 April 2018

1 reference

26 April 2018