A rapid screening system to determine drug affinities for the intestinal dipeptide transporter 2: affinities of ACE inhibitors. (Q52068884)

21 April 2018

title

A rapid screening system to determine drug affinities for the intestinal dipeptide transporter 2: affinities of ACE inhibitors. (English)

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21 April 2018

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21 April 2018

author name string

V A Moore

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21 April 2018

W J Irwin

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21 April 2018

P Timmins

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21 April 2018

S Chong

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21 April 2018

S A Dando

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21 April 2018

R A Morrison

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21 April 2018

language of work or name

English

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publication date

1 December 2000

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21 April 2018

International Journal of Pharmaceutics

published in

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21 April 2018

volume

210

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issue

1-2

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page(s)

29-44

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21 April 2018

Structural requirements for the intestinal mucosal-cell peptide transporter: the need for N-terminal alpha-amino group

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Intestinal transport of beta-lactam antibiotics: analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux

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Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2.

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Cefaclor uptake by the proton-dependent dipeptide transport carrier of human intestinal Caco-2 cells and comparison to cephalexin uptake

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Passive and carrier-mediated intestinal absorption components of two angiotensin converting enzyme (ACE) inhibitor prodrugs in rats: enalapril and fosinopril

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5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter

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Structural requirements for interaction with the oligopeptide transporter in Caco-2 cells

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Passive and carrier-mediated intestinal absorption components of captopril

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Mechanisms of transport of quinapril in Caco-2 cell monolayers: comparison with cephalexin

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Absorption of ACE inhibitors from small intestine and colon

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Distribution of the dipeptide transporter system along the gastrointestinal tract of rats based on absorption of a stable and specific probe, SQ-29852

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A rapid screening system to determine drug affinities for the intestinal dipeptide transporter 1: system characterisation.

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Suitability of enalapril as a probe of the dipeptide transporter system: in vitro and in vivo studies

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Characterization of the oral absorption of several aminopenicillins: determination of intrinsic membrane absorption parameters in the rat intestine in situ

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Configuration and preferential solid-state conformations of perindoprilat (S-9780). Comparison with the crystal structures of other ACE inhibitors and conclusions related to structure-activity relationships

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The role of an alpha-amino group on H+ -dependent transepithelial transport of cephalosporins in Caco-2 cells

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Structure-transport relationship for the intestinal small-peptide carrier: is the carbonyl group of the peptide bond relevant for transport?

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Molecular mechanism for the relative binding affinity to the intestinal peptide carrier. Comparison of three ACE-inhibitors: enalapril, enalaprilat, and lisinopril

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Molecular Determinants of Recognition for the Intestinal Peptide Carrier

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Angiotensin-converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco-2) cells

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Stability and in vitro absorption of captopril, enalapril and lisinopril across the rat intestine

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7 January 2021

10.1016/S0378-5173(00)00564-0

Identifiers

DOI

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21 April 2018

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21 April 2018