APPL, the Drosophila member of the APP-family, exhibits differential trafficking and processing in CNS neurons. (Q52047052)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764652%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

title

APPL, the Drosophila member of the APP-family, exhibits differential trafficking and processing in CNS neurons (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764652%20AND%20SRC:MED&resulttype=core&format=json

Beta amyloid protein precursor-like Dmel_CG7727

18 October 2019

main subject

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GOA release 2020-03-11

author name string

L Torroja

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579020&resulttype=core&format=json

15 May 2020

L Luo

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579020&resulttype=core&format=json

15 May 2020

K White

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579020&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

1 August 1996

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8764652%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

published in

Journal of Neuroscience

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15 May 2020

volume

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15 May 2020

issue

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15 May 2020

page(s)

4638-4650

1 reference

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Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

15 May 2020

cites work

1 reference

12 December 2020

Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).

1 reference

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Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals

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Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease

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Beta-amyloid precursor protein localization in the Golgi apparatus in neurons and oligodendrocytes. An immunocytochemical structural and ultrastructural study in normal and axotomized neurons

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A Drosophila receptor tyrosine phosphatase expressed in the embryonic CNS and larval optic lobes is a member of the set of proteins bearing the "HRP" carbohydrate epitope.

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A higher control center of locomotor behavior in the Drosophila brain.

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Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

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Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion

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The effect of heat shock on RNA synthesis in Drosophila tissues

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A Xenopus homologue of the human β-amyloid precursor protein: Development regulation of its gene expression

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Mushroom bodies and Drosophila learning

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beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

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Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse

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Monoclonal antibodies against the Drosophila nervous system

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Secretory processing of the Alzheimer amyloid beta/A4 protein precursor is increased by protein phosphorylation

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Activity labeling patterns in the medulla of Drosophila melanogaster caused by motion stimuli

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Ligand-dependent G protein coupling function of amyloid transmembrane precursor

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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The optic lobe of Drosophila melanogaster. II. Sorting of retinotopic pathways in the medulla.

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Drosophila mushroom body mutants are deficient in olfactory learning

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apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor

1 reference

12 December 2020

Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons

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12 December 2020

Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.

1 reference

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Genetic Transformation of Drosophila with Transposable Element Vectors

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Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

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12 December 2020

The Drosophila transcript encoded by the beta-amyloid protein precursor-like gene is restricted to the nervous system.

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12 December 2020

Microwave antigen retrieval of β-amyloid precursor protein immunoreactivity

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12 December 2020

Amyloid precursor protein in cortical neurons: coexistence of two pools differentially distributed in axons and dendrites and association with cytoskeleton

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12 December 2020

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

1 reference

12 December 2020

Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart

1 reference

12 December 2020

Expression of human Alzheimer amyloid precursor protein in insect cells

1 reference

12 December 2020

Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor

1 reference

12 December 2020

Regulation of proteolytic processing of the amyloid beta-protein precursor of Alzheimer's disease in transfected cell lines and in brain slices

1 reference

12 December 2020

The expression and processing of human beta-amyloid peptide precursors in Saccharomyces cerevisiae: evidence for a novel endopeptidase in the yeast secretory system

1 reference

12 December 2020

New heat shock puffs and beta-galactosidase activity resulting from transformation of Drosophila with an hsp70-lacZ hybrid gene

1 reference

12 December 2020

Distribution of an APP homolog, APLP2, in the mouse olfactory system: a potential role for APLP2 in axogenesis.

1 reference

12 December 2020

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

1 reference

12 December 2020

Proteolytic processing and secretion of human beta-amyloid precursor protein in yeast. Evidence for a yeast secretase activity.

1 reference

12 December 2020

Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density

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12 December 2020

Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene

1 reference

12 December 2020

The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis

1 reference

12 December 2020

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

12 December 2020

Expression of the amyloid protein precursor of Alzheimer's disease in the developing rat olfactory system.

1 reference

12 December 2020

Beta-amyloid precursor protein isoforms in various rat brain regions and during brain development

1 reference

12 December 2020

Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor

1 reference

12 December 2020

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

1 reference

12 December 2020

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

1 reference

12 December 2020

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

1 reference

12 December 2020

Immunocytochemical and learning studies of a Drosophila melanogaster neurological mutant, no-bridgeKS49 as an approach to the possible role of the central complex.

1 reference

12 December 2020

Characterization and cloning of fasciclin III: a glycoprotein expressed on a subset of neurons and axon pathways in Drosophila.

1 reference

12 December 2020

The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells

1 reference

12 December 2020

Amyloid precursor protein is localized in growing neurites of neonatal rat brain

1 reference

12 December 2020

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

1 reference

12 December 2020

Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells

1 reference

12 December 2020

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

1 reference

12 December 2020

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

12 December 2020

A Drosophila gene encoding a protein resembling the human beta-amyloid protein precursor

1 reference

12 December 2020

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

1 reference

12 December 2020

10.1523/JNEUROSCI.16-15-04638.1996

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579020&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579020&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579020&resulttype=core&format=json