Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor (Q51808669)

12 April 2018

title

Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor (English)

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12 April 2018

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12 April 2018

Roger J. Summers

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12 April 2018

author name string

Ekaterina Chernogubova

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12 April 2018

Masaaki Sato

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12 April 2018

Tore Bengtsson

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12 April 2018

publication date

7 April 2006

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12 April 2018

Naunyn-Schmiedeberg's Archives of Pharmacology

published in

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12 April 2018

volume

373

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12 April 2018

issue

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12 April 2018

page(s)

158-168

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12 April 2018

Respective degree of expression of beta 1-, beta 2- and beta 3-adrenoceptors in human brown and white adipose tissues

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ICI D7114 a novel selective β-adrenoceptor agonist selectively stimulates brown fat and increases whole-body oxygen consumption

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Beta 2-adrenergic receptor actions in neonatal and adult rat ventricular myocytes

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Functional identification of rat atypical beta-adrenoceptors by the first beta 3-selective antagonists, aryloxypropanolaminotetralins

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Ligand binding properties of putative beta 3-adrenoceptors compared in brown adipose tissue and in skeletal muscle membranes

21 January 2018

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beta(3)-Adrenoceptor agonists: potential, pitfalls and progress

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12 December 2020

Do beta 2-adrenergic receptors modulate Ca2+ in adult rat ventricular myocytes?

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Effects of several putative beta 3-adrenoceptor agonists on lipolysis in human omental adipocytes

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Markedly reduced effects of (-)-isoprenaline but not of (-)-CGP12177 and unchanged affinity of beta-blockers at Gly389-beta1-adrenoceptors compared to Arg389-beta1-adrenoceptors.

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12 December 2020

Influence of the beta 2-adrenergic agonist clenbuterol on insulin-stimulated lipogenesis in mouse adipocytes.

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12 December 2020

Stereoselectivity for interactions of agonists and antagonists at mouse, rat and human beta3-adrenoceptors

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12 December 2020

Mouse beta 3a- and beta 3b-adrenoceptors expressed in Chinese hamster ovary cells display identical pharmacology but utilize distinct signalling pathways

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12 December 2020

Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists

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12 December 2020

Canine ventricular myocyte beta2-adrenoceptors are not functionally coupled to L-type calcium current

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12 December 2020

Beta 1- and beta 2-adrenoceptor binding and functional response in right and left atria of rat heart

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12 December 2020

Beta 2-adrenoceptor activation by zinterol causes protein phosphorylation, contractile effects and relaxant effects through a cAMP pathway in human atrium

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12 December 2020

Comparison of beta adrenergic receptor subtypes in mammalian tissues

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12 December 2020

Selectivity and potency of agonists for the three subtypes of cloned human beta-adrenoceptors expressed in Chinese hamster ovary cells

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12 December 2020

Norepinephrine increases glucose transport in brown adipocytes via beta3-adrenoceptors through a cAMP, PKA, and PI3-kinase-dependent pathway stimulating conventional and novel PKCs.

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Potent and selective human beta(3)-adrenergic receptor antagonists

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Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs

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Enhanced cardiac L-type calcium current response to beta2-adrenergic stimulation in heart failure.

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Structural and conformational features determining selective signal transduction in the beta 3-adrenergic receptor

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12 December 2020

Alpha1- and beta1-adrenoceptor signaling fully compensates for beta3-adrenoceptor deficiency in brown adipocyte norepinephrine-stimulated glucose uptake

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Alternative splicing generates two isoforms of the beta3-adrenoceptor which are differentially expressed in mouse tissues.

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12 December 2020

Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes.

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12 December 2020

Selective activation of beta3-adrenoceptors by octopamine: comparative studies in mammalian fat cells

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Thermogenesis is beta3- but not beta1-adrenergically mediated in rat brown fat cells, even after cold acclimation

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Characterization of beta-adrenoceptor mediated smooth muscle relaxation and the detection of mRNA for beta1-, beta2- and beta3-adrenoceptors in rat ileum.

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Role of beta1- and beta2-adrenergic receptors in regulation of Cl- and Ca2+ channels in guinea pig ventricular myocytes

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Functional assessment of recombinant human alpha(2)-adrenoceptor subtypes with cytosensor microphysiometry

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The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors

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12 December 2020

Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells

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12 December 2020

Beta3-adrenoceptors in the cardiovascular system

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12 December 2020

Beta 1-adrenoceptor stimulation and beta 2-adrenoceptor stimulation differ in their effects on contraction, cytosolic Ca2+, and Ca2+ current in single rat ventricular cells

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12 December 2020

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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12 December 2020

An adipose tissue-specific beta-adrenergic receptor. Molecular cloning and down-regulation in obesity

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12 December 2020

beta1 to beta3 switch in control of cyclic adenosine monophosphate during brown adipocyte development explains distinct beta-adrenoceptor subtype mediation of proliferation and differentiation

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12 December 2020

Beta-adrenoceptors, but not alpha-adrenoceptors, stimulate AMP-activated protein kinase in brown adipocytes independently of uncoupling protein-1.

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12 December 2020

Prospects for beta 3-adrenoceptor agonists in the treatment of obesity and diabetes

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12 December 2020

Murine ventricular L-type Ca(2+) current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor

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12 December 2020

Comparison of the alpha-adrenoceptor-mediated effects of beta3-adrenoceptor ligands in rat pulmonary artery

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12 December 2020

Atypical beta-adrenoceptors mediating relaxation in the human colon: functional evidence for beta3-rather than beta4-adrenoceptors.

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12 December 2020

Response of Failing Canine and Human Heart Cells to β 2 -Adrenergic Stimulation

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12 December 2020

Aryloxypropanolamine and catecholamine ligand interactions with the beta(1)-adrenergic receptor: evidence for interaction with distinct conformations of beta(1)-adrenergic receptors.

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12 December 2020

Characterization of the beta-adrenoceptor subtype involved in mediation of glucose transport in L6 cells.

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12 December 2020

Differential relevance of beta-adrenoceptor subtypes in modulating the rat brown adipocytes function

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12 December 2020

Targeted disruption of the beta 3-adrenergic receptor gene.

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12 December 2020

Alpha- and beta-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture.

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12 December 2020

Beta-2 adrenergic activation of L-type Ca++ current in cardiac myocytes

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12 December 2020

Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2-adrenergic receptors

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12 December 2020

Inhibitory mechanism of BRL37344 on muscarinic receptor-mediated contractions of the rat urinary bladder smooth muscle

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12 December 2020

Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using extracellular acidification rate changes

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12 December 2020

Increase in insulin action and fat oxidation after treatment with CL 316,243, a highly selective beta3-adrenoceptor agonist in humans

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12 December 2020

Development of beta 3-adrenoceptor agonists for the treatment of obesity and diabetes--an update.

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12 December 2020

Coexisting beta-adrenoceptor subtypes: significance for thermogenic process in brown fat cells

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12 December 2020

Triiodothyronine and amiodarone effects on beta 3-adrenoceptor density and lipolytic response to the beta 3-adrenergic agonist BRL 37344 in rat white adipocytes

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12 December 2020

beta-Adrenergic regulation of IL-6 release from adipose tissue: in vivo and in vitro studies

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12 December 2020

Beta-1 receptor is the predominant beta-adrenoreceptor on rat brown adipose tissue

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12 December 2020

Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.

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12 December 2020

Effects of clenbuterol on insulin resistance in conscious obese Zucker rats

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12 December 2020

Binding of (-)-[3H]-CGP12177 at two sites in recombinant human beta 1-adrenoceptors and interaction with beta-blockers

1 reference

12 December 2020

Evidence for pleiotropic signaling at the mouse beta3-adrenoceptor revealed by SR59230A [3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanol oxalate].

1 reference

12 December 2020

10.1007/S00210-006-0056-3

Identifiers

DOI

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12 April 2018

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12 April 2018