Troglitazone, a peroxisome proliferator-activated receptor-gamma agonist, decreases tau phosphorylation in CHOtau4R cells (Q51806607)

12 April 2018

title

Troglitazone, a peroxisome proliferator-activated receptor-gamma agonist, decreases tau phosphorylation in CHOtau4R cells (English)

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12 April 2018

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Cristina d'Abramo

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12 April 2018

Roberta Ricciarelli

series ordinal

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12 April 2018

Maria A Pronzato

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12 April 2018

Peter Davies

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12 April 2018

language of work or name

English

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publication date

19 June 2006

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12 April 2018

Journal of Neurochemistry

published in

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12 April 2018

volume

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issue

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12 April 2018

page(s)

1068-1077

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12 April 2018

Role of peroxisome proliferator-activated receptor gamma in amyloid precursor protein processing and amyloid beta-mediated cell death.

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

21 January 2018

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Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

21 January 2018

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Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

21 January 2018

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Promotion of hyperphosphorylation by frontotemporal dementia tau mutations

21 January 2018

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Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

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Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

21 January 2018

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Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide.

21 January 2018

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Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

21 January 2018

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Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

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Receptor-independent actions of PPAR thiazolidinedione agonists: is mitochondrial function the key?

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Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

21 January 2018

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Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease.

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Post-translational modifications of tau protein in Alzheimer's disease

21 January 2018

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

21 January 2018

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Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling.

21 January 2018

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Defective brain microtubule assembly in Alzheimer's disease

21 January 2018

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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 January 2018

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"New"-clear functions of PDK1: beyond a master kinase in the cytosol?

21 January 2018

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T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities

21 January 2018

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Neurodegenerative tauopathies

21 January 2018

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Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

21 January 2018

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Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells.

21 January 2018

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Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain

21 January 2018

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Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function.

21 January 2018

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Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

21 January 2018

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The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes.

21 January 2018

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Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

21 January 2018

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First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

21 January 2018

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Cdk5 is a key factor in tau aggregation and tangle formation in vivo

21 January 2018

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Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease

21 January 2018

1 reference

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P70 S6 kinase mediates tau phosphorylation and synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03931.X

The modular phosphorylation and activation of p70s6k.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03931.X

Phosphorylation and activation of p70s6k by PDK1

21 January 2018

1 reference

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Unravelling the activation mechanisms of protein kinase B/Akt

21 January 2018

1 reference

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Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation

21 January 2018

1 reference

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Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more…

21 January 2018

1 reference

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Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies

21 January 2018

1 reference

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Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

21 January 2018

1 reference

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3-phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor-gamma and promotes adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03931.X

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03931.X

10.1111/J.1471-4159.2006.03931.X

21 January 2018

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DOI

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12 April 2018

release_hktvodmj7jalfmbxjhhp7tvjda

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12 April 2018