Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase. (Q51602379)

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20 March 2020

title

Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase (English)

1 reference

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20 March 2020

main subject

Plasmodium falciparum

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20 March 2020

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20 March 2020

Sundaram Balasubramanian

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20 March 2020

author name string

Lakshmeesha K Nagappa

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20 March 2020

Vasudeva S Prahlada Rao

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20 March 2020

Hemalatha Balaram

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20 March 2020

language of work or name

English

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publication date

13 August 2016

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20 March 2020

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20 March 2020

volume

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20 March 2020

issue

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20 March 2020

page(s)

1658-1669

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A point mutation at the subunit interface of hypoxanthine-guanine-xanthine phosphoribosyltransferase impairs activity: role of oligomerization in catalysis

20 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Identification of a single nucleotide substitution in the coding sequence of in vitro amplified cDNA from a patient with partial HPRT deficiency (HPRTBRISBANE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum

21 January 2018

1 reference

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Outwitting evolution: fighting drug-resistant TB, malaria, and HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Genome sequence of the human malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Purine and Pyrimidine Pathways as Targets in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Ternary complex structure of human hgprtase, prpp, mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Role of the flexible loop of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus in enzyme catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Genotype-phenotype correlations in Lesch-Nyhan disease: moving beyond the gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Site-directed mutagenesis using a single mutagenic oligonucleotide and DpnI digestion of template DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferase. Stability studies on the product-activated enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Purification and characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase and comparison with the human enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Comparison of multiple Amber force fields and development of improved protein backbone parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

VMD: visual molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

The contribution of cross‐links to protein stability: A normal mode analysis of the configurational entropy of the native state

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Structural and dynamical correlations in PfHGXPRT oligomers: A molecular dynamics simulation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.25107

21 January 2018

Identifiers

DOI

10.1002/PROT.25107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27479359%20AND%20SRC:MED&resulttype=core&format=json

release_nzqxkwg2nngmlavpshzhsroeie

20 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/nzqxkwg2nngmlavpshzhsroeie

mapped directly with Wikidata item

24 November 2022

based on heuristic

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