Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity. (Q51387149)

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scientific article published on 27 July 2005

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English	Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity.	scientific article published on 27 July 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity. (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

Mycobacterium tuberculosis

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Priscille Brodin

1

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

object named as

Roland Brosch

7

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object named as

Michael Nilges

5

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3

object named as

Laleh Majlessi

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

4

object named as

Claude Leclerc

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

Marien I. de Jonge

2

object named as

Marien I de Jonge

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

6

object named as

Stewart T Cole

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

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publication date

27 July 2005

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Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

number of pages

7

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based on heuristic

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

280

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Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

40

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Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

33953-33959

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Genomic interrogation of the dassie bacillus reveals it as a unique RD1 mutant within the Mycobacterium tuberculosis complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

A new evolutionary scenario for the Mycobacterium tuberculosis complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Genetic requirements for mycobacterial survival during infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Automated modeling of coiled coils: application to the GCN4 dimerization region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

MultiCoil: a program for predicting two- and three-stranded coiled coils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Protein-protein interactions of proteins from the ESAT-6 family of Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Stabilizing and destabilizing clusters in the hydrophobic core of long two-stranded alpha-helical coiled-coils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

NEMO trimerizes through its coiled-coil C-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

EsxA and EsxB are secreted by an ESAT-6-like system that is required for the pathogenesis of Staphylococcus aureus infections

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Decreased capacity of recombinant 45/47-kDa molecules (Apa) of Mycobacterium tuberculosis to stimulate T lymphocyte responses related to changes in their mannosylation pattern.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

CFP10 discriminates between nonacetylated and acetylated ESAT-6 of Mycobacterium tuberculosis by differential interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503515200

21 January 2018

Identifiers

10.1074/JBC.M503515200

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/16048998

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