UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells. (Q51146973)

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scientific article published on 17 March 2018

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English	UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells.	scientific article published on 17 March 2018

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PubMed publication ID

29549423

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20 March 2020

title

UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells (English)

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29549423

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20 March 2020

main subject

ceramides

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doxorubicin

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author

Marthe-Susanna Wegner

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1

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29549423

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20 March 2020

Peter Mattjus

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6

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29549423

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20 March 2020

Bing Peng

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9

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29549423

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Manuel Kaulich

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11

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29549423

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20 March 2020

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Nina Schömel

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2

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29549423

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20 March 2020

Lisa Gruber

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3

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29549423

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20 March 2020

Stephanie Beatrice Örtel

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4

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29549423

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20 March 2020

Matti Aleksi Kjellberg

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5

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29549423

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20 March 2020

Jennifer Kurz

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7

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29549423

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20 March 2020

Sandra Trautmann

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8

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29549423

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20 March 2020

Martin Wegner

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10

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29549423

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20 March 2020

Robert Ahrends

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12

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29549423

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20 March 2020

Gerd Geisslinger

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13

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29549423

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20 March 2020

Sabine Grösch

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14

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29549423

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20 March 2020

publication date

17 March 2018

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29549423

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20 March 2020

published in

Cellular and Molecular Life Sciences

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29549423

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20 March 2020

volume

75

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29549423

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20 March 2020

issue

18

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20 March 2020

page(s)

3393-3410

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20 March 2020

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CORRECTION: Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis

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Ceramide and glucosylceramide upregulate expression of the multidrug resistance gene MDR1 in cancer cells

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Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage

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D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein expression in A549 cells

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Doxorubicin influences the expression of glucosylceramide synthase in invasive ductal breast cancer

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Sphingomyelin synthase 1 activity is regulated by the BCR-ABL oncogene

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Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance

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The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.

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Ceramide kinase promotes tumor cell survival and mammary tumor recurrence

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Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

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Simplifying complexity: genetically resculpting glycosphingolipid synthesis pathways in mice to reveal function

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Lipid rafts as major platforms for signaling regulation in cancer

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Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy

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Tamoxifen regulation of sphingolipid metabolism--Therapeutic implications

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Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity

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12 December 2020

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The enigma of ceramide synthase regulation in mammalian cells

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12 December 2020

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Altered methylation of glucosylceramide synthase promoter regulates its expression and associates with acquired multidrug resistance in invasive ductal breast cancer

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Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide

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A Comprehensive High-Resolution Targeted Workflow for the Deep Profiling of Sphingolipids

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Identifiers

DOI

10.1007/S00018-018-2799-7

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PubMed publication ID

29549423

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29549423%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 March 2020

PubMed publication ID

29549423

1 reference

stated in

Europe PubMed Central

PubMed publication ID

29549423

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29549423%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 March 2020

 

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