Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris. (Q51125908)

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scientific article published on 23 February 2017

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English	Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris.	scientific article published on 23 February 2017

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3 April 2020

Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris (English)

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3 April 2020

Pichia pastoris

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Pichia pastoris

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Diethard Mattanovich

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3 April 2020

Brigitte Gasser

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3 April 2020

Friedrich Altmann

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3 April 2020

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Lukas Marsalek

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3 April 2020

Clemens Gruber

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3 April 2020

Markus Aleschko

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3 April 2020

Verena Puxbaum

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30 March 2017

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Biotechnology Journal

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3 April 2020

Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Cultivation strategies to enhance productivity of Pichia pastoris: A review

1 reference

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21 January 2018

Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris

1 reference

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The secretory pathway: exploring yeast diversity

1 reference

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Membrane trafficking in the yeast Saccharomyces cerevisiae model

1 reference

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Engineering of protein secretion in yeast: strategies and impact on protein production

1 reference

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Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae

1 reference

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Engineering of protein folding and secretion-strategies to overcome bottlenecks for efficient production of recombinant proteins

1 reference

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The yeast lysosome-like vacuole: endpoint and crossroads

1 reference

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Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae

1 reference

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21 January 2018

Novel Genes Involved in Endosomal Traffic in Yeast Revealed by Suppression of a Targeting-defective Plasma Membrane ATPase Mutant

1 reference

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21 January 2018

The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Identification of genes that enhance cellulase protein production in yeast

1 reference

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21 January 2018

Systematic screening of glycosylation- and trafficking-associated gene knockouts in Saccharomyces cerevisiae identifies mutants with improved heterologous exocellulase activity and host secretion

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Multistep processing of the secretion leader of the extracellular protein Epx1 in Pichia pastoris and implications for protein localization.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Causes of proteolytic degradation of secreted recombinant proteins produced in methylotrophic yeast Pichia pastoris: case study with recombinant ovine interferon-tau

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Disruption of YPS1 and PEP4 genes reduces proteolytic degradation of secreted HSA/PTH in Pichia pastoris GS115.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Identification and characterisation of novel Pichia pastoris promoters for heterologous protein production

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Identification and deletion of the major secreted protein of Pichia pastoris

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Pichia pastoris: protein production host and model organism for biomedical research

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Development of cysteine-free fluorescent proteins for the oxidative environment

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

A palette of fluorescent proteins optimized for diverse cellular environments

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Oxidative protein folding and unfolded protein response elicit differing redox regulation in endoplasmic reticulum and cytosol of yeast.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Top-down and bottom-up proteomics of SDS-containing solutions following mass-based separation

1 reference

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21 January 2018

The effect of temperature on the proteome of recombinant Pichia pastoris.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Directed evolution of a secretory leader for the improved expression of heterologous proteins and full-length antibodies in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Mapping of Vps21 and HOPS binding sites in Vps8 and effect of binding site mutants on endocytic trafficking

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

VPS21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Functional separation of endosomal fusion factors and the class C core vacuole/endosome tethering (CORVET) complex in endosome biogenesis

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Protease B of the lysosomelike vacuole of the yeast Saccharomyces cerevisiae is homologous to the subtilisin family of serine proteases

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

Proteinase B disruption is required for high level production of human mechano-growth factor in Saccharomyces cerevisiae.

1 reference

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21 January 2018

Protein secretion in Pichia pastoris and advances in protein production

1 reference

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21 January 2018

The proteolytic landscape of the yeast vacuole

1 reference

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21 January 2018

Tethering complexes in the endocytic pathway: CORVET and HOPS.

1 reference

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Enhanced protein secretion from multiprotease-deficient fission yeast by modification of its vacuolar protein sorting pathway.

1 reference

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21 January 2018

Enhanced peptide secretion by gene disruption of CYM1, a novel protease in Saccharomyces cerevisiae

1 reference

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21 January 2018

Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection

1 reference

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The CORVET subunit Vps8 cooperates with the Rab5 homolog Vps21 to induce clustering of late endosomal compartments

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

The N-terminal domains of Vps3 and Vps8 are critical for localization and function of the CORVET tethering complex on endosomes

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201600584

21 January 2018

An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking

1 reference

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21 January 2018

High-quality genome sequence of Pichia pastoris CBS7435

1 reference

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21 January 2018

Identifiers

10.1002/BIOT.201600584

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28230321%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28230321%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

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