TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation. (Q50792035)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15383523%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation (English)

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1 January 2020

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1 January 2020

Liusheng He

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1 January 2020

Xiaoli Wu

series ordinal

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1 January 2020

Peter E Lipsky

series ordinal

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1 January 2020

language of work or name

English

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publication date

21 September 2004

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Journal of Biological Chemistry

1 January 2020

published in

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1 January 2020

volume

279

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issue

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1 January 2020

page(s)

55855-55865

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A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

1 January 2020

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Structurally adaptive hot spots at a protein interaction interface on TRAF3.

21 January 2018

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Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway

21 January 2018

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Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

21 January 2018

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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

21 January 2018

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Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation.

21 January 2018

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CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization

21 January 2018

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High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization

21 January 2018

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4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB

21 January 2018

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Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation

21 January 2018

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Discrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kappaB pathways

21 January 2018

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Structurally Distinct Recognition Motifs in Lymphotoxin-β Receptor and CD40 for Tumor Necrosis Factor Receptor-associated Factor (TRAF)-mediated Signaling

21 January 2018

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Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor

21 January 2018

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TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase

21 January 2018

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TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

21 January 2018

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21 January 2018

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Cutting edge: profound defect in T cell responses in TNF receptor-associated factor 2 dominant negative mice.

21 January 2018

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Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.

21 January 2018

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

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TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses.

21 January 2018

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Membrane localization of TRAF 3 enables JNK activation

21 January 2018

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Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling

21 January 2018

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T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1).

21 January 2018

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

21 January 2018

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Both amino- and carboxyl-terminal domains of TRAF3 negatively regulate NF-kappaB activation induced by OX40 signaling

21 January 2018

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OX40-mediated memory T cell generation is TNF receptor-associated factor 2 dependent

21 January 2018

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Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling

21 January 2018

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TRAF-3 mRNA splice-deletion variants encode isoforms that induce NF-kappaB activation

21 January 2018

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Expression and function of TRAF-3 splice-variant isoforms in human lymphoma cell lines

21 January 2018

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Flow cytometric measurement of fluorescence (Förster) resonance energy transfer from cyan fluorescent protein to yellow fluorescent protein using single-laser excitation at 458 nm.

21 January 2018

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Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser.

21 January 2018

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A flow cytometric method to detect protein-protein interaction in living cells by directly visualizing donor fluorophore quenching during CFP-->YFP fluorescence resonance energy transfer (FRET).

21 January 2018

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A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study

21 January 2018

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Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.

21 January 2018

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Inhibition of NF-kappaB by ZAS3, a zinc-finger protein that also binds to the kappaB motif.

21 January 2018

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A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2

21 January 2018

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Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells

21 January 2018

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The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

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CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

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Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

21 January 2018

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TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

21 January 2018

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Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling

21 January 2018

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Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).

21 January 2018

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Lipid rafts are important for the association of RANK and TRAF6

21 January 2018

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Stress-induced decrease in TRAF2 stability is mediated by Siah2

21 January 2018

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Generation and analysis of Siah2 mutant mice.

21 January 2018

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Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

21 January 2018

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Tumor necrosis factor receptor (TNFR)-associated factor 2A (TRAF2A), a TRAF2 splice variant with an extended RING finger domain that inhibits TNFR2-mediated NF-kappaB activation

21 January 2018

1 reference

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An intact zinc ring finger is required for tumor necrosis factor receptor-associated factor-mediated nuclear factor-kappaB activation but is dispensable for c-Jun N-terminal kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407284200

21 January 2018

Identifiers

DOI

10.1074/JBC.M407284200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15383523%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

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