Spectrophotometric method for determination of bifunctional macrocyclic ligands in macrocyclic ligand-protein conjugates (Q50513647)

14 March 2018

title

Spectrophotometric method for determination of bifunctional macrocyclic ligands in macrocyclic ligand-protein conjugates (English)

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14 March 2018

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Dadachova E

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14 March 2018

Chappell LL

series ordinal

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14 March 2018

Brechbiel MW

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14 March 2018

publication date

1 November 1999

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14 March 2018

Nuclear Medicine and Biology

published in

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14 March 2018

volume

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issue

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page(s)

977-982

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14 March 2018

Improved synthesis of the bifunctional chelating agent 1,4,7,10-tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tri s(acetic acid)cyclododecane (PA-DOTA)

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Improved in vivo stability of actinium-225 macrocyclic complexes

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New anti-Cu-TETA and anti-Y-DOTA monoclonal antibodies for potential use in the pre-targeted delivery of radiopharmaceuticals to tumor

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Covalent attachment of chelating groups to macromolecules

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A facile, water-soluble method for modification of proteins with DOTA. Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates

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7 January 2021

Convenient synthesis of bifunctional tetraaza macrocycles

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7 January 2021

Conjugation of antibodies with bifunctional chelating agents: isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions

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7 January 2021

In vivo evaluation of a lead-labeled monoclonal antibody using the DOTA ligand

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7 January 2021

Copper chelates as probes of biological systems: stable copper complexes with a macrocyclic bifunctional chelating agent.

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Spectrophotometric method for the determination of a bifunctional DTPA ligand in DTPA-monoclonal antibody conjugates

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Monoclonal antibodies in diagnosis and therapy

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10.1016/S0969-8051(99)00054-2

Identifiers

DOI

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14 March 2018

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14 March 2018