Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate (Q50476254)

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scientific article published on 21 March 2014

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English	Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate	scientific article published on 21 March 2014

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

author name string

Kayode Ogungbenro

1

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

Leon Aarons

2

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

CRESim & Epi-CRESim Project Groups

3

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

publication date

21 March 2014

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

Journal of Pharmacokinetics and Pharmacodynamics

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

41

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Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

2

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

173-185

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Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy

1 reference

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Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy.

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The clinical pharmacology of 6-mercaptopurine

1 reference

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Quantitative justification for target concentration intervention--parameter variability and predictive performance using population pharmacokinetic models for aminoglycosides.

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Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia.

1 reference

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Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine

1 reference

https://api.crossref.org/works/10.1007%2FS10928-014-9355-3

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The interaction of 6-mercaptopurine (6-MP) and methotrexate (MTX).

1 reference

https://api.crossref.org/works/10.1007%2FS10928-014-9355-3

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Geometric method for measuring body surface area: a height-weight formula validated in infants, children, and adults

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CLINICAL CALORIMETRY

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21 January 2018

A priori prediction of tissue:plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery.

1 reference

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Mechanistic approaches to volume of distribution predictions: understanding the processes

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The fourth dimension of life: fractal geometry and allometric scaling of organisms.

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Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

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21 January 2018

Population-based mechanistic prediction of oral drug absorption

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21 January 2018

Physiologically based pharmacokinetic modeling of intestinal first-pass metabolism of CYP3A substrates with high intestinal extraction.

1 reference

https://api.crossref.org/works/10.1007%2FS10928-014-9355-3

21 January 2018

Plasma and Erythrocyte Concentrations of Mercaptopurine after Oral Administration in Children

1 reference

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21 January 2018

A formula to estimate the approximate surface area if height and weight be known. 1916.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mammalian xanthine oxidase by folate compounds and amethopterin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

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The effect of methotrexate on the bioavailability of oral 6-mercaptopurine

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics of oral 6-mercaptopurine and intravenous 6-mercaptopurine riboside in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacologic observations on 6-mercaptopurine and 6-methylthiopurine ribonucleoside

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large interindividual variations in the pharmacokinetics of oral 6-mercaptopurine in maintenance therapy of children with acute leukaemia and non-Hodgkin lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of mercaptopurine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of oral methotrexate and mercaptopurine in children with lower risk acute lymphoblastic leukemia: a joint children's cancer group and pediatric oncology branch study

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variable bioavailability of oral mercaptopurine. Is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and clinical pharmacological study of mercaptopurine administered as a prolonged intravenous infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

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Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

based on heuristic

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Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651962

12 December 2020

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Age-related changes in laboratory values used in the diagnosis of anemia and iron deficiency

1 reference

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inferred from PubMed ID database lookup

Physiologically based pharmacokinetics of cyclosporine A: extension to tissue distribution kinetics in rats and scale-up to human

1 reference

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Identifiers

10.1007/S10928-014-9355-3

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/24651962

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