Breast cancer type 1 susceptibility protein homolog CELE_C36A4.8 (Q50301538)

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protein found in Caenorhabditis elegans

• Breast cancer type 1 susceptibility protein homolog
• brc-1

edit

Language	Label	Description	Also known as
English	Breast cancer type 1 susceptibility protein homolog CELE_C36A4.8	protein found in Caenorhabditis elegans	Breast cancer type 1 susceptibility protein homolog brc-1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

10 April 2019

UniProt protein ID

B6VQ60

subclass of

protein

1 reference

stated in

UniProt

retrieved

31 January 2018

UniProt protein ID

B6VQ60

part of

BRCT domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/B6VQ60

Zinc finger, RING/FYVE/PHD-type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/B6VQ60

Breast cancer type 1 susceptibility protein (BRCA1)

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/B6VQ60

Zinc finger, RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, C3HC4 RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

BRCT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

stated in

UniProt

retrieved

10 April 2019

UniProt protein ID

B6VQ60

encoded by

brc-1

1 reference

stated in

UniProt

retrieved

10 April 2019

UniProt protein ID

B6VQ60

molecular function

DNA binding

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

ubiquitin-protein transferase activity

determination method or standard

IEA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=B6VQ60&geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

protein binding

determination method or standard

IPI

2 references

retrieved

1 January 2018

stated in

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IPI

retrieved

1 January 2018

stated in

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IPI

zinc ion binding

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

transferase activity

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

metal ion binding

determination method or standard

IEA

2 references

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

ubiquitin protein ligase activity

determination method or standard

IDA

1 reference

retrieved

1 January 2018

stated in

A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites.

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IDA

ubiquitin-protein transferase activity

determination method or standard

IBA

IEA

2 references

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

cell component

nucleus

determination method or standard

IEA

2 references

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

chromosome

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

cytoplasm

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

plasma membrane

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

BRCA1-BARD1 complex

determination method or standard

IDA

1 reference

retrieved

27 February 2018

stated in

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=B6VQ60&geneProductId=UniProtKB:B6VQ60

determination method or standard

IDA

BRCA1-A complex

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

BRCA1-BARD1 complex

determination method or standard

IBA

IDA

2 references

retrieved

1 January 2018

stated in

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IDA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

biological process

double-strand break repair via homologous recombination

determination method or standard

IGI

IMP

3 references

retrieved

27 February 2018

stated in

BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair.

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=B6VQ60&geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

27 February 2018

stated in

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=B6VQ60&geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

27 February 2018

stated in

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=B6VQ60&geneProductId=UniProtKB:B6VQ60

determination method or standard

IGI

DNA repair

determination method or standard

IEA

IMP

3 references

retrieved

1 January 2018

stated in

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

nucleotide-excision repair

determination method or standard

IGI

IMP

2 references

retrieved

1 January 2018

stated in

DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

1 January 2018

stated in

DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IGI

apoptotic process

determination method or standard

IMP

1 reference

retrieved

1 January 2018

stated in

BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair.

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

cellular response to DNA damage stimulus

determination method or standard

IEA

IMP

3 references

retrieved

1 January 2018

stated in

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

cell cycle

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

protein ubiquitination

determination method or standard

IDA

IEA

2 references

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IEA

retrieved

1 January 2018

stated in

A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites.

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IDA

positive regulation of histone acetylation

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

negative regulation of histone acetylation

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

regulation of cell population proliferation

determination method or standard

IBA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=B6VQ60&geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

negative regulation of fatty acid biosynthetic process

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

positive regulation of transcription by RNA polymerase II

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

meiotic chromosome separation

determination method or standard

IMP

1 reference

retrieved

1 January 2018

stated in

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

double-strand break repair via homologous recombination

determination method or standard

IBA

IGI

IMP

4 references

retrieved

1 January 2018

stated in

BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair.

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

1 January 2018

stated in

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

1 January 2018

stated in

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IGI

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IBA

mitotic sister chromatid segregation

determination method or standard

IGI

1 reference

retrieved

1 January 2018

stated in

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IGI

embryo development ending in birth or egg hatching

determination method or standard

IGI

IMP

2 references

retrieved

1 January 2018

stated in

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

retrieved

1 January 2018

stated in

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IGI

cellular response to ionizing radiation

determination method or standard

IMP

1 reference

retrieved

1 January 2018

stated in

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

GOA

curator

UniProt

UniProt protein ID

B6VQ60

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B6VQ60

determination method or standard

IMP

has part(s)

Zinc finger, RING-type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/B6VQ60

BRCT domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/B6VQ60

Zinc finger, RING-type, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/B6VQ60

Zinc finger, C3HC4 RING-type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/B6VQ60

Identifiers

RefSeq protein ID

NP_001254881

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

175499

NP_001254882

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

175499

UniProt protein ID

B6VQ60

1 reference

stated in

UniProt

retrieved

10 April 2019

UniProt protein ID

B6VQ60

Ensembl protein ID

C36A4.8a

1 reference

stated in

ensembl Release 96

Ensembl protein ID

C36A4.8a

C36A4.8b

1 reference

stated in

ensembl Release 96

Ensembl protein ID

C36A4.8b

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q50301538&oldid=2030330674"