Zonisamide: Pharmacology and Clinical Efficacy in Epilepsy (Q50098766)

24 February 2018

title

Zonisamide: Pharmacology and Clinical Efficacy in Epilepsy (English)

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24 February 2018

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Yoshinobu Masuda

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24 February 2018

Masayuki Ishizaki

series ordinal

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24 February 2018

Masanao Shimizu

series ordinal

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24 February 2018

publication date

1 December 1998

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24 February 2018

CNS Neuroscience & Therapeutics

published in

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24 February 2018

volume

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24 February 2018

issue

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24 February 2018

page(s)

341-360

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24 February 2018

Oxygen free radicals and Parkinson's disease

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Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

21 January 2018

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Selective vulnerability in the gerbil hippocampus: morphological changes after 5-min ischemia and long survival times

21 January 2018

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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

21 January 2018

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Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

21 January 2018

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Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain

21 January 2018

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Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

21 January 2018

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Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes

21 January 2018

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Chronic parkinsonism secondary to intravenous injection of meperidine analogues

21 January 2018

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Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy

21 January 2018

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Mechanism and pathogenesis of ischemia-induced neuronal damage

21 January 2018

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Zonisamide reduces hypoxic-ischemic brain damage in neonatal rats irrespective of its anticonvulsive effect

21 January 2018

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Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice

21 January 2018

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Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse

21 January 2018

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Differential antagonism of denzimol to various components of metrazol-induced seizures in rats and mice.

21 January 2018

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Effects of zonisamide (AD-810) on tungstic acid gel-induced thalamic generalized seizures and conjugated estrogen-induced cortical spike-wave discharges in cats

21 January 2018

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New insights into the cause of Parkinson's disease

21 January 2018

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Delayed neuronal death in the gerbil hippocampus following ischemia

21 January 2018

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MPTP toxicity: implications for research in Parkinson's disease

21 January 2018

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Zonisamide for progressive myoclonus epilepsy: long-term observations in seven patients

21 January 2018

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Behavioural effects and supersensitivity in the rat following intranigral MPTP and MPP+ administration

21 January 2018

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

21 January 2018

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Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

21 January 2018

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New antiepileptic drugs. II. Clinical use.

21 January 2018

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Relationships Between Plasma Concentrations of Diphenylhydantoin, Phenobarbital, Carbamazepine, and 3-Sulfamoylmethyl-1,2-Benzisoxazole (AD-810), a New Anticonvulsant Agent, and Their Anticonvulsant or Neurotoxic Effects in Experimental Animals

21 January 2018

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Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.

21 January 2018

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Protective effect of zonisamide, an antiepileptic drug, against transient focal cerebral ischemia with middle cerebral artery occlusion-reperfusion in rats

21 January 2018

1 reference

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The anticonvulsant zonisamide scavenges free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

21 January 2018

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Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

21 January 2018

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Cognitive deficits induced by global cerebral ischaemia: relationship to brain damage and reversal by transplants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Zonisamide as a neuroprotective agent in an adult gerbil model of global forebrain ischemia: a histological, in vivo microdialysis and behavioral study

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Increased striatal lipid peroxidation after intracerebroventricular MPP+ administration to mice

21 January 2018

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Blockade of sustained repetitive action potentials in cultured spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant

21 January 2018

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Zonisamide enhances slow sodium inactivation in Myxicola

21 January 2018

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Zonisamide for add-on treatment of refractory partial epilepsy: a European double-blind trial.

21 January 2018

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Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma

21 January 2018

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The metabolism of N-alkyl-4-bromobenzenesulfonamides in the mouse. Correlation with anticonvulsant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Long-term observation of rats after unilateral intra-amygdaloid injection of kainic acid

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Experimental complex partial seizures induced by a microinjection of kainic acid into limbic structures

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Studies on 3-substituted 1,2-benzisoxazole derivatives. 6. Syntheses of 3-(sulfamoylmethyl)-1,2-benzisoxazole derivatives and their anticonvulsant activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Chronic Focal Epileptiform Discharges Induced by Injection of Iron Into Rat and Cat Cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

Detection of free radicals during brain ischemia and reperfusion by spin trapping and microdialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.1998.TB00075.X

10.1111/J.1527-3458.1998.TB00075.X

21 January 2018

Identifiers

DOI

1 reference

24 February 2018

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24 February 2018