B cells in type 1 diabetes mellitus and diabetic kidney disease. (Q50077505)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29038537%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

3 references

31 August 2020

27 January 2021

24 June 2021

B cells in type 1 diabetes mellitus and diabetic kidney disease (English)

1 reference

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7 April 2020

2 references

29 May 2020

31 August 2020

3 references

31 August 2020

27 January 2021

24 June 2021

insulin-secreting cells

1 reference

27 January 2021

1 reference

24 June 2021

Mia J Smith

1 reference

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7 April 2020

Kimber M Simmons

series ordinal

1 reference

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7 April 2020

John C Cambier

series ordinal

1 reference

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7 April 2020

language of work or name

English

0 references

publication date

1 October 2017

1 reference

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Nature Reviews Nephrology

7 April 2020

17 October 2017

3 references

31 August 2020

27 January 2021

24 June 2021

4 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29038537%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

31 August 2020

27 January 2021

24 June 2021

1 reference

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7 April 2020

issue

1 reference

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7 April 2020

page(s)

712-720

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Breakdown in peripheral tolerance in type 1 diabetes in mice and humans

7 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Genetics, pathogenesis and clinical interventions in type 1 diabetes

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1 reference

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Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Can rodent models of diabetic kidney disease clarify the significance of early hyperfiltration?: recognizing clinical and experimental uncertainties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Mechanisms of diabetic hyperfiltration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Temporal profile of diabetic nephropathy pathologic changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Predominant autoantibody production by early human B cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

B-cell tolerance checkpoints in health and autoimmunity

21 January 2018

1 reference

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B-cell anergy: from transgenic models to naturally occurring anergic B cells?

21 January 2018

1 reference

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Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

21 January 2018

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Silencing of autoreactive B cells by anergy: a fresh perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Identification of anergic B cells within a wild-type repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

B-lymphocyte depletion with rituximab and β-cell function: two-year results

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Lymphopenia and autoimmunity: A double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Development of autoantibodies in the TrialNet Natural History Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

B-cell cross-presentation of autologous antigen precipitates diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

The Use of Electrochemiluminescence Assays to Predict Autoantibody and Glycemic Progression Toward Type 1 Diabetes in Individuals with Single Autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

ECL-IAA and ECL-GADA Can Identify High-Risk Single Autoantibody-Positive Relatives in the TrialNet Pathway to Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Rituximab does not reset defective early B cell tolerance checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Analysis of islet inflammation in human type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

B Cell Receptor Affinity for Insulin Dictates Autoantigen Acquisition and B Cell Functionality in Autoimmune Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: a population-based study in the United Kingdom

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Genetics of type 1A diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

PTPN2-deficiency exacerbates T follicular helper cell and B cell responses and promotes the development of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Cellular and humoral immune responses in the early stages of diabetic nephropathy in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Increased CD4(+)CXCR5(+)T follicular helper cells in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Oxidized LDL-anti-oxidized LDL immune complexes and diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Circulating immune complexes among diabetic children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Oxidized LDL immune complexes stimulate collagen IV production in mesangial cells via Fc gamma receptors I and III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

OxLDL immune complexes activate complement and induce cytokine production by MonoMac 6 cells and human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Low serum C4 concentrations: an inherited predisposition to insulin dependent diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Diabetic nephropathy and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

TLR1/2, TLR7, and TLR9 Signals Directly Activate Human Peripheral Blood Naive and Memory B Cell Subsets to Produce Cytokines, Chemokines, and Hematopoietic Growth Factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Urinary and renal interstitial concentrations of TNF-alpha increase prior to the rise in albuminuria in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Cytokine-producing B lymphocytes-key regulators of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Genetic Variants of PTPN2 Gene in Chinese Children with Type 1 Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Roles of the NF-kappaB pathway in lymphocyte development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Targeting CD22 reprograms B-cells and reverses autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

CD4(+)CD25(+) T-cells control autoimmunity in the absence of B-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Contribution of Receptor Editing to the Antibody Repertoire

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

21 January 2018

12 December 2020

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Development of type 1 diabetes despite severe hereditary B-cell deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Reciprocal regulation of polarized cytokine production by effector B and T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Investigation of the role of B-cells in type 1 diabetes in the NOD mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Prevalence of antibodies to nucleic acids in insulin-dependent diabetics and their relatives

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Cross-reactivity of anti-ssDNA antibodies with heparan sulfate in patients with type I diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Diabetic glomerulonephropathy: histopathologic, immunofluorescent, and ultrastructural studies of 16 cases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.138

Immune and inflammatory role in renal disease.

31 March 2020

1 reference

12 December 2020

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice

1 reference

12 December 2020

Histopathological assessment of renal biopsy specimens of subjects with urine abnormality

1 reference

12 December 2020

Low plasma C4 concentrations: association with microangiopathy in insulin dependent diabetes

1 reference

12 December 2020

Interleukin-6 and C-reactive protein in pathogenesis of diabetic nephropathy: new evidence linking inflammation, glycemic control, and microalbuminuria.

1 reference

12 December 2020

B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.

1 reference

12 December 2020

High levels of circulating interleukin-10 in diabetic nephropathy patients

1 reference

12 December 2020

Interleukin-10-1082A/G polymorphism and diabetic nephropathy: a meta-analysis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2017.138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29038537%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29038537%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

PubMed publication ID

29038537

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29038537%20AND%20SRC:MED&resulttype=core&format=json