Clinical significance of PD-1/PD-Ls gene amplification and overexpression in patients with hepatocellular carcinoma (Q59792829)

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14 April 2020

title

Clinical significance of PD-1/PD-Ls gene amplification and overexpression in patients with hepatocellular carcinoma (English)

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14 April 2020

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hepatocellular carcinoma

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Li-Jie Ma

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14 April 2020

Fei-Ling Feng

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14 April 2020

Liang-Qing Dong

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14 April 2020

Zhao Zhang

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14 April 2020

Meng Duan

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14 April 2020

Long-Zi Liu

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14 April 2020

Jie-Yi Shi

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14 April 2020

Liu-Xiao Yang

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14 April 2020

Zhi-Chao Wang

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14 April 2020

Shu Zhang

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14 April 2020

Zhen-Bin Ding

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14 April 2020

Ai-Wu Ke

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14 April 2020

Ya Cao

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14 April 2020

Xiao-Ming Zhang

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14 April 2020

Jian Zhou

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14 April 2020

Jia Fan

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14 April 2020

Xiao-Ying Wang

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14 April 2020

Qiang Gao

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14 April 2020

publication date

10 November 2018

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14 April 2020

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volume

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issue

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14 April 2020

page(s)

5690-5702

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Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma

14 April 2020

cites work

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12 December 2020

Hallmarks of Cancer: The Next Generation

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12 December 2020

Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas

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12 December 2020

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

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12 December 2020

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer

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12 December 2020

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

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12 December 2020

Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab

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12 December 2020

Comprehensive molecular characterization of gastric adenocarcinoma

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12 December 2020

Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

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12 December 2020

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

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12 December 2020

Intrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinoma

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12 December 2020

Immunotherapy: PD-1-PD-L1 axis: efficient checkpoint blockade against cancer

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12 December 2020

A copy number variation map of the human genome

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12 December 2020

Current concepts of immune based treatments for patients with HCC: from basic science to novel treatment approaches

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12 December 2020

Immune checkpoint blockade: a common denominator approach to cancer therapy

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12 December 2020

PD-L1 protein expression in breast cancer is rare, enriched in basal-like tumours and associated with infiltrating lymphocytes

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12 December 2020

Localized and systemic approaches to treating hepatocellular carcinoma.

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12 December 2020

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

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12 December 2020

Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies

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12 December 2020

PD-L1 copy number gain in nonsmall-cell lung cancer defines a new subset of patients for anti PD-L1 therapy

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12 December 2020

Regulation of PD-L1: a novel role of pro-survival signalling in cancer.

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12 December 2020

Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial

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12 December 2020

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas

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12 December 2020

PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome

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12 December 2020

Pan-cancer analysis of copy number changes in programmed death-ligand 1 (PD-L1, CD274) - associations with gene expression, mutational load, and survival.

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12 December 2020

Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.

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12 December 2020

Programmed death ligand 1 expression in hepatocellular carcinoma: Relationship With clinical and pathological features.

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12 December 2020

Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer.

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12 December 2020

PD-L1 expression as a predictive biomarker for cytokine-induced killer cell immunotherapy in patients with hepatocellular carcinoma

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12 December 2020

Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents.

1 reference

12 December 2020

Overexpression and gene amplification of PD-L1 in cancer cells and PD-L1+ immune cells in Epstein-Barr virus-associated gastric cancer: the prognostic implications

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12 December 2020

Pembrolizumab as first-line therapy for patients with PD-L1-positive advanced non-small cell lung cancer: a phase 1 trial

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12 December 2020

A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non-Small Cell Lung Cancer

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12 December 2020

PD-L1, Galectin-9 and CD8+ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma

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12 December 2020

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

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12 December 2020

Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with recurrent carcinoma of the anal canal.

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12 December 2020

Safety and tolerability of pembrolizumab in patients with relapsed/refractory primary mediastinal large B-cell lymphoma.

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12 December 2020

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.

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12 December 2020

The effect of PD-L1 testing on the cost-effectiveness and economic impact of immune checkpoint inhibitors for the second-line treatment of NSCLC.

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12 December 2020

Critical appraisal of Chinese 2017 guideline on the management of hepatocellular carcinoma.

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12 December 2020

Diverse modes of clonal evolution in HBV-related hepatocellular carcinoma revealed by single-cell genome sequencing.

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12 December 2020

Regulation and Function of the PD-L1 Checkpoint.

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12 December 2020

Landscape of immune microenvironment in hepatocellular carcinoma and its additional impact on histological and molecular classification

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12 December 2020

Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial

1 reference

12 December 2020

Prevalence of PDL1 Amplification and Preliminary Response to Immune Checkpoint Blockade in Solid Tumors

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12 December 2020

Identifiers

DOI

10.7150/THNO.28742

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14 April 2020

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14 April 2020

PubMed publication ID

30555574

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