The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules. (Q59211381)

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scientific article published on 30 October 2008

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English	The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules.	scientific article published on 30 October 2008

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Europe PubMed Central

PMC publication ID

6363534

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1 July 2019

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http://europepmc.org/abstract/PMC/6363534

title

The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules. (English)

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Europe PubMed Central

PMC publication ID

6363534

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1 July 2019

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http://europepmc.org/abstract/PMC/6363534

main subject

exocytosis

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author

Karine Crozat

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4

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6363534

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1 July 2019

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http://europepmc.org/abstract/PMC/6363534

Sergio D Catz

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8

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6363534

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1 July 2019

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Agnieszka A Brzezinska

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1

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6363534

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Jennifer L Johnson

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2

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6363534

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Daniela B Munafo

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3

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6363534

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Bruce Beutler

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5

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6363534

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William B Kiosses

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6

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6363534

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http://europepmc.org/abstract/PMC/6363534

Beverly A Ellis

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7

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6363534

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publication date

30 October 2008

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6363534

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1 July 2019

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http://europepmc.org/abstract/PMC/6363534

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Traffic

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6363534

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http://europepmc.org/abstract/PMC/6363534

volume

9

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6363534

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1 July 2019

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http://europepmc.org/abstract/PMC/6363534

issue

12

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Europe PubMed Central

PMC publication ID

6363534

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1 July 2019

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http://europepmc.org/abstract/PMC/6363534

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2151-2164

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6363534

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ImageJ

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11 June 2022

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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6363534/fullTextXML

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Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle.

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Rab27a is required for regulated secretion in cytotoxic T lymphocytes

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12 December 2020

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The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain

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PubMed

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12 December 2020

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Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport

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12 December 2020

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Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

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Identification of an organelle receptor for myosin-Va

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12 December 2020

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A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport

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12 December 2020

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Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin

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12 December 2020

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Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells

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12 December 2020

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Interaction of the actin cytoskeleton with microtubules regulates secretory organelle movement near the plasma membrane in human endothelial cells.

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12 December 2020

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Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

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Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.

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12 December 2020

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The small GTPase Rab27B regulates amylase release from rat parotid acinar cells

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12 December 2020

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Rac2 is critical for neutrophil primary granule exocytosis.

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

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Membrane proteinase 3 expression and ANCA-induced neutrophil activation

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

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Primate defensins

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

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inferred from PubMed ID database lookup

Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18939952

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic analysis of human neutrophil granules

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

based on heuristic

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Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18939952

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

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Bad signals jam organelle traffic

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12 December 2020

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Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

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12 December 2020

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Rab27b regulates mast cell granule dynamics and secretion

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12 December 2020

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Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis

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12 December 2020

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Mechanism of adenovirus neutralization by Human alpha-defensins

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12 December 2020

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Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse

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45 Measurement of O2− production by human neutrophils. The preparation and assay of NADPH oxidase-containing particles from human neutrophils

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Cell-to-cell communication and ovulation. A study of the cumulus-oocyte complex

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12 December 2020

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based on heuristic

inferred from PubMed ID database lookup

Granules of the human neutrophilic polymorphonuclear leukocyte.

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12 December 2020

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Chemoattractant-induced release of elastase by lipopolysaccharide (LPS)-primed neutrophils; inhibitory effect of the anti-inflammatory drug nimesulide

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12 December 2020

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inferred from PubMed ID database lookup

Azurophilic granules of human neutrophilic leukocytes are deficient in lysosome-associated membrane proteins but retain the mannose 6-phosphate recognition marker.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/18939952

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

DOI

10.1111/J.1600-0854.2008.00838.X

1 reference

stated in

Europe PubMed Central

PMC publication ID

6363534

retrieved

1 July 2019

reference URL

http://europepmc.org/abstract/PMC/6363534

PMC publication ID

6363534

1 reference

stated in

Europe PubMed Central

PMC publication ID

6363534

retrieved

1 July 2019

reference URL

http://europepmc.org/abstract/PMC/6363534

PubMed publication ID

18939952

1 reference

stated in

Europe PubMed Central

PMC publication ID

6363534

retrieved

1 July 2019

reference URL

http://europepmc.org/abstract/PMC/6363534

 

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